Words similar to knockout
Example sentences for: knockout
How can you use “knockout” in a sentence? Here are some example sentences to help you improve your vocabulary:
To identify cases where M. incognita and C. elegans share homologous genes which have been surveyed in C. elegans for knockout phenotype using RNAi, a list of all 7,212 available C. elegans RNAi experiments (5 May 2002) from WormBase [ 56 ] was compared to the list of all M. incognita clusters with significant homology matches to the C. elegans Wormpep v.54 protein database.
In the lens, alpha-crystallin also associates with type III intermediate filament proteins and the beaded filament proteins CP49 and CP115, and correct beaded filament assembly has been shown depend on the presence of alpha-crystallin [ 16 ] . Beaded filament mRNA levels are greatly increased in differentiating lens epithelium and have been suggested as a pan-specific marker for lens fiber development [ 17 ] . Alpha-crystallin has also been shown to interact directly with DNA [ 18 ] . In transfected CHO cells, alphaB has also been shown to ectopically localize to interphase nuclei, suggesting a role for this protein in the nucleus [ 19 ] . A nuclear role for alphaB in the lens was supported by the findings that a subset of lens epithelial cells derived from alphaB knockout mice demonstrated hyperproliferation and genomic instability [ 20 ] . In addition, the administration of exogenous alpha-crystallin to primary bovine lens epithelial cell cultures resulted in the formation of lentoid bodies, consistent with a role for these proteins in lens differentiation [ 21 ] . These findings indicate that alpha-crystallin may have a multitude of in vivo functions.
5 [ 61 ] . This suggests that the effect of gp130 knockout on cardiac development is mediated outside of cardiac tissue and the primary developmental defect is peripheral to the heart.
Ginny, for example, could turn into a knockout in Book 5, when she should be 14 or so, winning--too late--the hitherto impermeable heart of Potter, then extracting just revenge by scorning him utterly, sending him off on a quixotic love-quest just when he's most needed to save the world.
By including whole-plant water relations and also metabolite measurements, the use of transgenic plants, preferably of the 'gene knockout' type, will yield a greater understanding and prevent errors of interpretation that could arise from simply correlating single-gene knockouts with changes in hydraulic conductivity parameters.
Loading...