Example sentences for: knockouts

How can you use “knockouts” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Although no murine knockouts of subunits of P-TEFb have been reported, DRB and flavopiridol, two ATP analogs that inhibit the kinase activity of CDK9, can inhibit nearly all transcription by RNAPII in human cells [29].

  • Thus, populations derived from ‘knockouts’ express phenotypic variation that was not expressed by the wild-type network, suggesting that any of the genes within the network may buffer genetic variation.

  • For example, through the use of STAT5-/- mice, Ihle et al have been able to identify those IL-2 target genes that require STAT5 [ 56 57 ] . Similar approaches with mutant signaling proteins, knockouts, or over-expression systems enable such dissection of the signal transduction pathways leading to specific target genes.

  • Nursed on boxing and Hollywood, Americans imagine fights as choreography, a dance of elegant combinations, roundhouse kicks, clean knockouts.

  • Disease-causing myocilin mutants are less soluble in Triton [ 16 ] and are retained by the cell [ 12 ] . Other studies have shown that a truncated form of myocilin does not get secreted [ 20 21 ] and that mouse MYOC knockouts are without discernable phenotype [ 42 ] . Furthermore, a human hemizygous individual containing an interstitial deletion of chromosome 1, which encodes MYOC , was without evidence of glaucoma [ 43 ] and another patient homozygous for a severly truncated form of myocilin had no evidence of glaucoma [ 44 ] or other discernable phenotypes.


How many words do you know? Try our free vocabulary size test!


Search

Search for example sentences

Loading Loading...
Quantcast