Example sentences for: kinetochore

How can you use “kinetochore” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Vertebrate shugoshin has been shown to have a strong microtubule-binding domain [36] and is found at the kinetochore [37].

  • CENP-E binds to the kinetochore throughout mitosis and to MTs of the spindle mid-zone during late stages of mitosis [ 20].

  • Proteasome activity is required for germinal vesicle breakdown (GVBD) in starfish and toad oocytes [ 44 45 ] and for activating Xenopus oocytes [ 45 46 ] . Also, proteasomes are needed for regulating centrosome segregation [ 38 47 ] , kinetochore structure [ 39 ] , and sister chromatid cohesion and separation [ 48 ] . When rat oocytes were exposed to the proteasome inhibitor MG132, proteasomes translocated to the meiotic spindle, MPF activity was sustained, and oocytes were arrested in MI with partially segregated chromosomes [ 42 ] .

  • Ndc10 forms part of a structure known as the kinetochore, which forms around the centromere and is responsible for the attachment to the spindle; establishment and maintenance of cohesion at pericentric regions may therefore rely on both the centromere sequence and kinetochore function [13,20].


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