Words similar to junctional
Example sentences for: junctional
How can you use “junctional” in a sentence? Here are some example sentences to help you improve your vocabulary:
Carbenoxolone, the succinyl ester of glycyrrhetinic acid [ 1 ] , is now used in clinical treatment of ulcer diseases [ 2 ] . It has some pharmacological properties such as: the inhibition of 11β-hydroxy steroid dehydrogenase (11β-HSD) [ 1 ] , and inhibition of gap junctional intercellular communication [ 3 ] . Electrotonic synaptic communication between neurons via gap junctions (GJs) is increasingly recognized as an important synchronizing mechanism in the brain.
Indeed, a rapid search of the Online Mendelian Inheritance in Man database (OMIM [ 18]) for genes associated with the terms 'severe' and 'disorder' confirmed that mutations of GALC, LAMB3, GJB2, JAG1, TGFBI, LPL and LDLR were the origin of serious disorders: Krabbe disease, Herlitz junctional epidermolysis bullosa, autosomal dominant deafness - Vohwinkel syndrome, Alagille syndrome, corneal dystrophy, type I hyperlipoproteinemia and hypercholesterolemia, respectively.
It is also worth considering that the elongated shape of the lateral forming cells becomes much more extreme as development proceeds (Fig 4) [ 8 ] . This brings the laterals close to the cell edges that are parallel to the proximal distal axis of the central core and the junctional complexes at these edges could provide orientation guidance.
In this way wild type laterals resemble fz mutant wing cells [ 5 ] . Thus, early in their development laterals are not close to the junctional complex or the prominent cortical cytoskeleton at the cell periphery and are unlikely to be getting any orientation guidance in this way.
The assembly of the hair at the cell periphery puts it in close proximity to the junctional complex perhaps allowing for direct interactions between the cortical and hair cytoskeletons [ 5 ] . This could provide orientation guidance for the growing hair.
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