Example sentences for: junctional

How can you use “junctional” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The assembly of the hair at the cell periphery puts it in close proximity to the junctional complex perhaps allowing for direct interactions between the cortical and hair cytoskeletons [ 5 ] . This could provide orientation guidance for the growing hair.

  • Carbenoxolone, the succinyl ester of glycyrrhetinic acid [ 1 ] , is now used in clinical treatment of ulcer diseases [ 2 ] . It has some pharmacological properties such as: the inhibition of 11β-hydroxy steroid dehydrogenase (11β-HSD) [ 1 ] , and inhibition of gap junctional intercellular communication [ 3 ] . Electrotonic synaptic communication between neurons via gap junctions (GJs) is increasingly recognized as an important synchronizing mechanism in the brain.

  • The pathogenesis of abnormal neuronal synchrony underlying seizures, formerly thought to be based mainly on the chemical synaptic transmission, now includes a role of gap junctional communication.

  • Indeed, a rapid search of the Online Mendelian Inheritance in Man database (OMIM [ 18]) for genes associated with the terms 'severe' and 'disorder' confirmed that mutations of GALC, LAMB3, GJB2, JAG1, TGFBI, LPL and LDLR were the origin of serious disorders: Krabbe disease, Herlitz junctional epidermolysis bullosa, autosomal dominant deafness - Vohwinkel syndrome, Alagille syndrome, corneal dystrophy, type I hyperlipoproteinemia and hypercholesterolemia, respectively.

  • The cells preserved their apical junctional complexes and well developed intercellular gap junctions.


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