Words similar to junctional
Example sentences for: junctional
How can you use “junctional” in a sentence? Here are some example sentences to help you improve your vocabulary:
Indeed, a rapid search of the Online Mendelian Inheritance in Man database (OMIM [ 18]) for genes associated with the terms 'severe' and 'disorder' confirmed that mutations of GALC, LAMB3, GJB2, JAG1, TGFBI, LPL and LDLR were the origin of serious disorders: Krabbe disease, Herlitz junctional epidermolysis bullosa, autosomal dominant deafness - Vohwinkel syndrome, Alagille syndrome, corneal dystrophy, type I hyperlipoproteinemia and hypercholesterolemia, respectively.
The primary generative mechanism is V(D)J recombination, the rearrangement of B-cell receptor (BCR) or T-cell receptor (TCR) V, D, and J gene segments to form functional genes; the resulting combinatorial and junctional diversity can produce around 10 14BCR specificities and around 10 18TCR specificities in one animal [ 37].
Carbenoxolone, the succinyl ester of glycyrrhetinic acid [ 1 ] , is now used in clinical treatment of ulcer diseases [ 2 ] . It has some pharmacological properties such as: the inhibition of 11β-hydroxy steroid dehydrogenase (11β-HSD) [ 1 ] , and inhibition of gap junctional intercellular communication [ 3 ] . Electrotonic synaptic communication between neurons via gap junctions (GJs) is increasingly recognized as an important synchronizing mechanism in the brain.
The pathogenesis of abnormal neuronal synchrony underlying seizures, formerly thought to be based mainly on the chemical synaptic transmission, now includes a role of gap junctional communication.
It is also worth considering that the elongated shape of the lateral forming cells becomes much more extreme as development proceeds (Fig 4) [ 8 ] . This brings the laterals close to the cell edges that are parallel to the proximal distal axis of the central core and the junctional complexes at these edges could provide orientation guidance.
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