Words similar to jak

Example sentences for: jak

How can you use “jak” in a sentence? Here are some example sentences to help you improve your vocabulary:

Janus kinase JAK
Signaling proceeds through the Janus kinase/signal transducers and activators of transcription (JAK/STAT) or the ras-mitogen-activated protein (MAP) kinase pathways [for a review see [ 7 ] ].
Further, both the SHP-2/Ras and JAK/STAT3 pathways are activated by IL-6R/gp130 signaling (Fig.
Several signaling events, including the activation of Jak kinases 1 and 3 are shared among the 'common γ chain' cytokines [ 50 ] . Other signaling events, such as the activation of Shc, Gab2, SHP-2 and MAPK, are shared among IL-2 and 15, but not the other common γ chain cytokine receptors, and Tyr 388 of IL-2Rβ appears critical for these events [ 51 ] . Despite these signaling similarities, it is clear that the biological properties of IL-2 are unique among the common γ chain cytokines, as the other cytokines cannot compensate for IL-2 in the IL-2 knockout mouse [ 52 ] . In addition, IL-15 appears uniquely critical for the development of NK cells, as evidenced by the phenotypes of IL-15 [ 53 ] and IL-15R α [ 54 ] deficient mice.
The now-activated JAK2 phosphorylates STAT3, which forms homodimers, can cross the nuclear membrane and function as a transcription factor, inducing various genes including genes involved in the cellular transformation process [ 15 ] .