Words similar to jak

Example sentences for: jak

How can you use “jak” in a sentence? Here are some example sentences to help you improve your vocabulary:

The JAK/STAT signaling pathway is involved in many cytokines, hormones, and growth factors mediated signaling pathways to regulate a variety of biological responses, including development, cell differentiation, proliferation and survival [ 7 8 ] . Once STAT proteins are activated by tyrosine-phosphorylation, form homo or heterodimers that are translocated to the nucleus, where they can bind to specific sequences in the DNA, thereby stimulating gene transcription.
Further experiments are underway to determine if STAT3 requires phosphorylation by a different kinase, such as JAK1, in NRP-154 cells.
A possible explanation of the data would be the use of JAK1 for phosphorylation of STAT3 in NRP-154 cells, which would not be inhibited by AG490.
Inhibition of JAK2 induced apoptosis in NRP-152 but not NRP-154 clones
Our data imply that JAK2-mediated phosphorylation of STAT3 was essential for the survival of NRP-152 cells, but that NRP-154 cells did not require activated JAK2 for survival, regardless of amount of IL-6 produced by the cell.