Words similar to jak

Example sentences for: jak

How can you use “jak” in a sentence? Here are some example sentences to help you improve your vocabulary:

Further, both the SHP-2/Ras and JAK/STAT3 pathways are activated by IL-6R/gp130 signaling (Fig.
Janus kinase JAK
A possible explanation of the data would be the use of JAK1 for phosphorylation of STAT3 in NRP-154 cells, which would not be inhibited by AG490.
The JAK/STAT signaling pathway is involved in many cytokines, hormones, and growth factors mediated signaling pathways to regulate a variety of biological responses, including development, cell differentiation, proliferation and survival [ 7 8 ] . Once STAT proteins are activated by tyrosine-phosphorylation, form homo or heterodimers that are translocated to the nucleus, where they can bind to specific sequences in the DNA, thereby stimulating gene transcription.
IL-6 receptor binding activates JAK1 as well as JAK2, which in turn phosphorylates STAT3 [ 14 ] . This in fact has been shown to be the case for v-src-transformed fibroblasts [ 34 ] . Another hypothesis is that STAT3 activation in NRP-154 cells is not dependent upon a signaling cascade, but is constitutive, possibly due to a mutation not unlike that contained within the cSTAT3 plasmid generated by Bromberg, et al.