Example sentences for: jak-mediated

How can you use “jak-mediated” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Most frequently, poor MHCII inducibility in response to IFNg has been attributed to alterations in the IFNg signalling pathway and epigenetic silencing of gene expression (reviewed in Ref [ 13 ] ). The cascade of IFNg signalling events leading to transcription activation of MHCII genes has been characterized in great detail (reviewed in Ref [ 30 ] ). Binding of IFNg to its receptor results in JAK-mediated phosphorylation of STAT1 on Tyrosine 701.

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