Example sentences for: jab

How can you use “jab” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • These 31 probe sets are derived from 27 unique genes, and most likely represent bona fide IL-2 targets, since the group includes the genes JAB/SSI-1/SOCS-1, flt3 ligand, IL-2Rp55, caspase 3, and p78, which have already been reported as IL-2-induced genes.

  • Cyclin A, but not cyclin E levels were also suppressed by MIB in an AR-dependent manner, while the levels of the COP9/signalosome subunit CSN5/JAB1 and tubulin remained constant (Fig.

  • In humans the SWIRM domain is found linked to a JAB1/PAD1 catalytic domain, suggesting that this protein may serve as a link in the regulation of chromatinic proteins through proteasomal degradation.

  • In vertebrates, the SWIRM domain is found fused along with a Myb (SANT) domain to a JAB1/PAD1 domain [ 48, 49] (for example, in the human protein KIAA1915, Figure 2).

  • While our study suggests that SKP2 is an important player in p27 regulation in prostate cancer cells, recent studies have also implicated another protein, CSN5/JAB1, in p27 regulation [ 54 55 ] . CSN5 is a subunit of the COP9/signalosome (CSN) complex [ 56 57 58 59 ] , but also forms distinct complexes apparently lacking CSN subunits [ 55 60 61 62 ] . Overexpression of CSN5 in NIH3T3 cells causes p27 export from the nucleus and ectopic degradation [ 54 ] . Notably, like SKP2 [ 33 36 37 38 ] , CSN5 was found to be overexpressed in cancers devoid of p27 [ 63 ] . However, our studies did not reveal any effect of MIB on CSN5 expression.


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