Example sentences for: isoprenoids

How can you use “isoprenoids” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The theoretical link between statins and ROCK1 goes as follows: statins inhibit the isoprenoid pathway, isoprenoids are regulators of the enzyme Rho, and Rho in turn activates ROCK1.

  • In further support of a role for isoprenoids, we were able to demonstrate that supplementation of cells with mevalonate abolished statin-activated shedding (see Figure 4).

  • We do not yet know which (if any) other “cholesterol-related” Alzheimer phenomena are also attributable to modulation of isoprenoids, Rho, or ROCK.

  • Through the action of farnesyl transferases and type I geranylgeranyl transferases, isoprenoids are attached to the amino acid sequence Cys-Ala-Ala-Xaa (“CAAX”) at the C-terminus of the Rho family of GTPases [20].

  • These data are consistent with a role for isoprenoids in statin control of APP metabolism in cultured cells.


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