Example sentences for: interfering

How can you use “interfering” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • CC-1065 (Figure 1) is among the most potent antitumor agents discovered [ 9 10 11 12 13 ] . It binds to double-stranded B-DNA within the minor groove with a sequence preference for 5'-d(A/GNTTA)-3' and 5'-d(AAAAA)-3', and alkylates the N3 position of the 3'-adenine with its left-hand CPI segment [ 14 15 ] . CC-1065 also inhibits gene transcription by interfering with binding of the TATA box-binding protein to its target DNA [ 16 ] . Despite its high potency and broad spectrum of antitumor activity, CC-1065 cannot be used in humans because it causes delayed death in experimental animals [ 17 ] . To pursue compounds possessing the potent antitumor activity but devoid of the toxic side effects of the parent compound, many CC-1065 analogues have been synthesized [ 18 19 20 21 22 23 24 25 26 ] .

  • The reactivity of ERα monoclonal antibody in lane 10 (ERα h-151) indicates a distinct band at 66 kDa (green arrowhead, 66α), not interfering with the ~64 band identified by E12 antibody and ~64 and 68 kDa bands identified by F12 antibody.

  • The RNase III orthologue "Dicer" (Figure 1) plays a central role in RNA interference (RNAi) by cleaving dsRNAs to ~21 bp fragments, termed small interfering(si) RNAs.

  • systems demonstrated that 21–23 nucleotide ‘short interfering'RNAs (siRNAs), derived from cutting longer dsRNA, can guide mRNA cleavage (Zamore et al.

  • It was reported that PPAR activation could down-regulate the activity of AP-1 by interfering with the functions of c-jun [ 36 37 ] . Therefore, the following set of experiments was designed to test if PPAR activation could reduce c-jun activation in 25-OH-cholesterol treated microglia.


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