Words similar to inteins
Example sentences for: inteins
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Multiple sequence alignments of diverse intein sequences identified eight motifs composed of moderately conserved residues [ 18 28 ] . The A-ATPase A subunit of the Thermoplasma and Pyrococcus intein multiple sequence alignment (with manual modification) is shown in figure 1. The T. acidophilum intein (173 amino acids long) is among the shortest inteins known, and the alignment with other inteins reveals the absence of sequences homologous to the typical endonuclease motifs.
The A-ATPase and the V-ATPase inteins are located in the most conserved part of the host gene.
Using PSI-BLAST [ 27 ] with different inteins as seeds, divergent inteins with less than ten percent sequence identity as compared to the query sequence are recovered (data not shown); however, using this approach we did not discover any additional intein or homing endonuclease encoding genes in T. acidophilum.
Thermoplasma acidophilum is among sixteen archaea for which inteins have been reported to date (Intein database http://www.neb.com/inteins/int_reg.html [ 18 ] ). Members of the genus Thermoplasma lack cell walls and possess a cytoskeleton.
Inteins without this domain perform autocatalytic splicing [ 15 16 ] . Homing endonucleases and the process of homing have been more intensively studied in self splicing introns [ 17 ] , and the process is assumed to be similar for inteins.