Words similar to inteins
Example sentences for: inteins
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The sequences removed during splicing are called inteins (short for internal protein); the portions of the host protein are termed exteins (external protein) [ 3 4 5 ] .
The significance of the match between the T. acidophilum and the three pyrococcal ATPase inteins was assessed using PRSS at http://fasta.bioch.virginia.edu/fasta/prss.htm [ 29 ] . The P-value for this match, i.e. the probability of obtaining a match of this quality by chance alone, was calculated to be below 10 -10.
Moreover, these inteins are inserted into the same highly conserved sequence in the ATP binding site.
This phenomenon, called protein splicing, was first discovered about a decade ago in the Saccharomyces cerevisiae V-ATPase catalytic subunit A [ 6 7 ] . Intein excision depends on the splicing domain of the intein and the first amino acid residue of the C-extein [ 8 ] . The inteins known to date are between 134 and 608 amino acids long, and they have been reported from all three domains of life: eukaryotes, eubacteria and archaea.
1) shows that the T. acidophilum and T. volcanium inteins do not contain an endonuclease domain.
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