Words similar to integrin
Example sentences for: integrin
How can you use “integrin” in a sentence? Here are some example sentences to help you improve your vocabulary:
We investigated the interaction of TGFβ 1 with the α V β 6 integrin and its influence on selected target genes known to be involved in cell cycle-regulated growth inhibition.
To test the latter hypothesis, we compared the total β1 integrin distribution with the distribution of the fraction of β1 integrins complexed with CD98 on HT 1080 cells (Fig.
Despite the molecular level of our understanding of integrin activation, a number of key questions remain unresolved.
Spectrin and protein 4.1 form a complex with actin filaments [ 17 26 ] that may be important in signaling in additional to forming a physical link between the cytoskeletal network and the cell membrane [ 27 ] . Furthermore, PI4K activity has been shown to associate with the actin cytoskeleton by biochemical detergent extraction [ 28 ] and is thought to specifically localize with α3β1 integrin [ 29 ] . PI4K catalyzes the production of phosphatidylinositol-4-phosphate, an intermediate in multiple phosphatidylinositol signaling pathways which itself can interact with actin binding proteins to regulate microfilament polymerization [ 30 ] . Our work now suggests that the mRNAs of these proteins are all positioned in close association with the actin cytoskeleton to permit efficient localization of their protein products.
The interaction of the α4β7 integrin on a subset of T cells, with its ligand, MAdCAM-1, on high venular and lymphoid endothelial cells has been shown to be support the entry of of these lymphocytes into the gut in IBD [ 8].
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