Words similar to inhibits
Example sentences for: inhibits
How can you use “inhibits” in a sentence? Here are some example sentences to help you improve your vocabulary:
While IL-1 promotes cartilage degradation through MMP synthesis and inhibits matrix deposition by reducing Col2A1 gene expression, TGF-β has the opposite effect on chondrocytes [ 3].
Sp1 is important for the basal expression of various collagens, and blocking Sp1 broadly inhibits expression of ECM genes [ 8 ] . Terms such as 'Pathologic neovascularization' (13,9) and 'Vascular endothelium' (29,26) can refer to processes of angiogenesis, the generation of new blood vessels from preexisting vessels for the delivery of nutrients to tumors.
Rapamycin inhibits activation of p70 S6 kinase, a downstream effector in the PI 3-kinase signaling pathway [ 13 ] . Rapamycin forms a complex with FK506-binding protein 12 and this complex blocks the kinase activity of mTOR (mammalian target of rapamycin), a kinase upstream of p70 S6 kinase [ 20 ] . The IC 50 for p70 S6 kinase inhibition by rapamycin is ~0.
2)) play a crucial role [ 9 10 ] . ATP produced by the metabolism of glucose inhibits K ATP activity, resulting in development of depolarization responsible for opening of L-type Ca 2+channels, allowing Ca 2+influx.
Interestingly, inhibition of Rho-p160ROCK has recently been shown to give similar lymphocyte morphology as inhibition of Rho with C3 [ 50 ] . Another interesting candidate may be p120 PKN, as recent studies have established that PKN phosphorylates cytoskeletal intermediate filaments [ 47 ] and is directly linked to the cytoskeletal network through associations with α-actinin [ 48 ] . Also, PKN may be involved in relating cytoplasmic signals to the nucleus, for in response to stress, nuclear translocation of PKN occurs [ 49 ] . This is particularly important in light of previous work demonstrating that inactivation of Rho in peripheral blood T lymphocytes inhibits costimulatory signals up-regulating IL-2 production [ 25 ] . Future experiments will focus on determining the relationship of Rho GTPases and the regulation of T cell morphology [ 25 51 52 ] .
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