Example sentences for: infectivity

How can you use “infectivity” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Data presented here show that CAP remains bound to HIV-1 after removal of unreacted compound, impairing virus infectivity due to blockade of binding sites for cellular coreceptors CXCR4 and CCR5.

  • The MAPK acts by stimulating AP-1 and a subsequent physical and functional interaction of AP-1 with NF-κB, resulting in a complex that synergistically transactivates the HIV-1 [ 60 ] . At the level of infection and entry, the activation of MAPK through the Ras/Raf/MEK (MAPK kinase) signaling pathway enhances the infectivity of HIV-1 virions.

  • The percentage of residual infectivity after CAP/sCD4 treatment was calculated from calibration curves relating absorbance to virus dilutions of untreated viruses.

  • Earlier studies describing the underlying molecular mechanisms involved in the HIV-1 inhibitory effect of the candidate microbicide CAP indicated that this compound remains bound to HIV-1, impairing virus infectivity by blockade of binding sites for cellular coreceptors CXCR4 and CCR5 [ 8 ] . Results reported here further extend these findings and show that: 1) there is synergism between sCD4 and CAP for inhibition of virus infectivity; 2) CAP binding to HIV-1 leads to conformational changes in viral envelope glycoproteins resulting in the expression of functionally inert six-helix bundle structures.

  • Lentiviruses like HIV possess a gene that encodes an protein called Vif (‘viral infectivity factor’) that counters APOBEC3G (Sheehy et al.


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