Example sentences for: infection

How can you use “infection” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Converging evidence from epidemiological and molecular studies suggests that infection of genital human papillomavirus (HPV) is causally linked to the development of CC [ 4 ] . Since only a small fraction of HPV-infected cervical intra-epithelial neoplastic (CIN) lesions progress to invasive cancer, these studies further suggest that in addition to HPV, other host genetic factors play a role in cervical carcinogenesis [ 5 ] . A number of molecular studies have identified genetic alterations in these two histologic types of CC and at various stages of precursor lesions [ 6 7 8 ] . Despite this molecular characterization, the genetic basis of CC initiation and progression is still very poorly understood.

  • It is likely that differences in the transcriptional program would emerge at later stages of infection, as wild-type and actA bacteria replicate and kill the cells, and prfA do not.

  • TNFα and TNFβ have been extensively studied and are involved in immune and pro-inflammatory responses, playing an important role in host defenses against infection and other disease states [ 4 5 6 7 ] . The biological effects of TNFα and TNFβ are mediated through the two membrane associated receptors, TNFR1 (p55) and TNFR2 (p75), that are expressed on the target cells [ 8 9 ] . The postulated pathogenic roles for TNF include sepsis and other bacterial and viral pathologies [ 10 11 12 ] , certain cancers [ 13 ] , metastasis [ 14 ] and chronic autoimmune disorders such as rheumatoid arthritis [ 15 16 ] , multiple sclerosis [ 17 ] and Crohn's disease [ 18 ] . It is worth noting that TNFα mutants have been identified that selectively bind TNFR1.

  • Secondary infection was defined as the identification of a new site of infection or the emergence of a different organism at the same site, generally requiring a change in antibiotic management.

  • Among patients with blood stream infection, survivors had a lower APACHE II score than nonsurvivors (median, 17 vs. 27.


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