Words similar to immunosuppression
Example sentences for: immunosuppression
How can you use “immunosuppression” in a sentence? Here are some example sentences to help you improve your vocabulary:
Evidence has been accumulated that TGFβ promotes late-stage tumorigenesis by stimulating angiogenesis and invasive behaviour of tumor cells, enhancing immunosuppression and supporting epithelial-mesenchymal transition of cancer cells [ 4 ] . Furthermore, TGFβ is believed to be part of a vicious circle in bone metastases as it gets released from osteoclast-degraded bone substance and subsequently stimulates PTHrP gene expression in nearby metastatic cancer cells which in turn leads to an activation of osteoclastic bone resorption [ 11 ] . Therefore, it is of great interest to understand in more detail the molecular aspects of TGFβ-mediated gene expression in metastatic breast cancer cells and to explore ways to interfere with this tumorigenic signalling.
Current study supports our hypothesis that the immunosuppression results in an increased expression of cyclin inhibitor p21, which by inhibiting the expression of cyclins controls the allo-immune activation.
Due to this, interpretation of colonic biopsies for intestinal A-GVHD may be a major diagnostic challenge especially for those not conversant with these findings [ 10 ] . Only a few studies have statistically evaluated the diagnostic significance of some histopathological features [ 6 ] . A-GVHD is treated with immunosuppression which may worsen an underlying infective condition.
Severe hepatic disease was the leading chronic illness, followed by immunosuppression, severe respiratory illness, renal illness and cardiovascular illness.
New drug regimens capable of inducing tolerance to the transplanted islets would allow recipients to maintain their grafts without general immunosuppression and its associated toxicities.
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