Example sentences for: immunosuppression

How can you use “immunosuppression” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Latent CMV in many organs can be reactivated from its dormant state by several means of immunosuppression, including transmission from donors to immunosuppressed recipients of transplants, and blood transfusion.

  • The pulmonary complications are also likely to vary according to geographic locations, HIV risk factor, and severity of immunosuppression.

  • Looked at another way, patients with heart, liver, lung, or kidney failure have a dismal prognosis for survival, so the toxicity associated with immunosuppression is warranted (the benefits of graft survival outweigh the risks associated with the medications).

  • Evidence has been accumulated that TGFβ promotes late-stage tumorigenesis by stimulating angiogenesis and invasive behaviour of tumor cells, enhancing immunosuppression and supporting epithelial-mesenchymal transition of cancer cells [ 4 ] . Furthermore, TGFβ is believed to be part of a vicious circle in bone metastases as it gets released from osteoclast-degraded bone substance and subsequently stimulates PTHrP gene expression in nearby metastatic cancer cells which in turn leads to an activation of osteoclastic bone resorption [ 11 ] . Therefore, it is of great interest to understand in more detail the molecular aspects of TGFβ-mediated gene expression in metastatic breast cancer cells and to explore ways to interfere with this tumorigenic signalling.

  • Due to this, interpretation of colonic biopsies for intestinal A-GVHD may be a major diagnostic challenge especially for those not conversant with these findings [ 10 ] . Only a few studies have statistically evaluated the diagnostic significance of some histopathological features [ 6 ] . A-GVHD is treated with immunosuppression which may worsen an underlying infective condition.


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