Words similar to immunomodulatory
Example sentences for: immunomodulatory
How can you use “immunomodulatory” in a sentence? Here are some example sentences to help you improve your vocabulary:
Breastfeeding is associated with a lower incidence of infant diarrhoea and respiratory disease, particularly in less developed countries [ 1 ] . A recent ecological study on breastfeeding showed that more than half of all infant deaths from diarrhoeal disease and acute respiratory infections in Latin America are preventable by exclusive breastfeeding in infants aged 0-3 months and partial breastfeeding throughout the remainder of infancy [ 2 ] . The theoretical basis for this may be a combination of the nutritional and immunomodulatory effects of human milk [ 3 ] . Since 2001, the WHO recommends exclusive breastfeeding up to the age of 6 months (World Health Assembly Resolution 55.
These include using various adjuvants, such as incomplete Freund's adjuvant and immunomodulatory agents, such as IL-12 [4], GM-CSF [5], anti-CTLA-4 Abs [35], or heat shock proteins [36].
The drugs have been studied with relation to their effect in Graves' hyperthyroidism which, like psoriasis, is an autoimmune disorder [ 9 10 11 12 ] Antithyroid thioureylenes, of which propylthiouracil, methimazole and carbimazole are used in clinical practice, have known immunomodulatory properties [ 13 14 ] and, in the case of psoriasis, also have antiproliferative effects as demonstrated by their ability to produce a decline in markers of cellular proliferation such as proliferative cell nuclear antigen (PCNA) [ 15 ] .
We advocate that such immunomodulatory approaches be tested first in controlled models where the results can be appropriately attributed to the agent itself.
DEK is a nuclear protein that is not structurally related to any known family of proteins [ 12 13 ] . Although it may also participate in DNA replication and RNA processing [ 14 15 ] , we have identified DEK as a DNA-binding protein that recognizes the TG-rich peri- ets (pets) regulatory element in the human immunodeficiency virus type 2 (HIV-2) enhancer [ 16 ] . The pets site is important in mediating HIV-2 enhancer stimulation in activated T cells and monocytes [ 17 18 19 ] , suggesting that DEK may play an immunomodulatory role as it participates in transcriptional activation through this and related sites.
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