Words similar to immunomarker
Example sentences for: immunomarker
How can you use “immunomarker” in a sentence? Here are some example sentences to help you improve your vocabulary:
However, as demonstrated in our previous study, it is not uncommon to face an equivocal situation when S-100 protein is used as an immunomarker for the interpretation of single melanoma micrometastases in sentinel lymph nodes [ 6 ] . Based on our previous study with HMB45 [ 6 ] and an initial study with micropthalmia transcription factor [ 22 ] , these immunomarkers were not considered suitable for inclusion in the cocktail due to the immunoreactivity of non-melanoma cells in the sentinel lymph nodes.
Thus, a highly sensitive immunomarker such as S-100 is less effective for interpretation of sentinel lymph nodes for melanoma micrometastases (especially when present as single cells) than MART-1 and Melan-A [ 6 ] . Certain morphological features help to differentiate melanoma cells and other non-melanoma cells such as S100 immunoreactive dendritic cells in sentinel lymph nodes.
If the primary melanoma is non-immunoreactive for 'the cocktail', the negative interpretation of the sentinel lymph nodes with cocktail in this situation may be confirmed with other suitable immunomarker to which the primary melanoma is immunoreactive.
Tyrosinase alone or any other immunomarker used individually, would be less sensitive than a cocktail.
The possibility of using a cocktail of these monoclonal antibodies for the evaluation of melanoma sentinel lymph node would require only one section as compared to three adjacent sections for each of the immunomarker, with resultant cost savings of approximately two thirds.
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