Words similar to ibd
Example sentences for: ibd
How can you use “ibd” in a sentence? Here are some example sentences to help you improve your vocabulary:
Previous positional cloning studies have revealed three genes associated with IBD that carry variants with a causative role.
Several studies have indicated that T helper (Th1) immune response has important roles in the development of IBD [ 48 49 50 ] . Moreover, dysregulation of cytokine networks is involved in Th1-dominant immune responses in IBD [ 48 49 50 ] . Among the Th1 cytokines, TNF-α is thought to be perhaps the most important cytokine responsible for driving the onset and evolution of IBD.
MAdCAM-1 is normally expressed in the gut, and its expression is dramatically amplified during inflammation [ 2 3 ] . The functional significance of increased appearance of MAdCAM-1 in IBD is supported by several reports which show that immunoneutralization of either MAdCAM-1 or its ligand, the α4β7 integrin, attenuate inflammation and mucosal damage in animal models of colitis [ 8 9 10 ] . However, since monoclonal antibodies directed against other ECAMs, particularly VCAM-1, can as well reduce disease activity in colitis models [ 11 12 13 14 ] , the literature suggests that MAdCAM-1 is probably necessary, but insufficient for the maximal penetrance of experimental and probably also clinical IBD.
There was an imbalance between over- and underexpressed genes in the IBD subtypes.
IL-10) treatment is now being developed for experimental colitis and human IBD.