Example sentences for: ibat

How can you use “ibat” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Increased bile acid transport in cftr (-/-) mice is associated with an increase in the abundance of IBAT protein in the brush border membrane.

  • A 1:20 dilution of anti-IBAT protein antibodies was applied for one hour.

  • IBAT: ileal bile acid transporter; CFTR: cystic fibrosis transmembrane conductance regulator.

  • An alternative mechanism for the upregulation of IBAT in cystic fibrosis is that CFTR acts as a negative regulator of IBAT, as it does for the epithelial sodium channel [ 36 ] . As IBAT is a sodium-dependent apical membrane transporter, it might be regulated by CFTR, as is the epithelial sodium channel (ENaC) present in the apical membrane of the ileal enterocyte.

  • The correlation between zygosity and level of IBAT protein expression suggests a close relationship between the function of the CFTR chloride channel and the sodium-dependent ileal bile acid transporter.


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