Words similar to hyperplastic

Example sentences for: hyperplastic

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As expected, phosphorylated AKT was undetectable in hyperplastic ducts, in tumors from Wnt-1 TG, Pten +/+ mice, and tumors from Wnt-1 TG, Pten +/- mice that retained the wild type allele (Fig.
There was no difference in staining between the ducts that were proximal to the tumor and those that were more distal, and neither were there any differences in staining observed between histologically normal and hyperplastic ducts in any of the samples analyzed (data not shown).
However, in both intervention and regression trials, significant CD4 +T cell and CD8 +T cell infiltration into hyperplastic/dysplastic islets and tumors was noted in Rip1-Tag2 mice that had received the combination of sub-lethal radiation and adoptive transfer of TCR splenocytes.
Several weeks later, a spontaneous autoimmune response to Tag is readily detectable, with significant lymphocyte infiltration of hyperplastic/dysplastic islets.
The mice show systemic tolerance to Tag, mounting neither humoral nor cellular immune responses to Tag upon immunization of purified protein [ 25 26 ] . Rip1-Tag2 mice display a reproducible pattern of multistage tumor development, from normal islets to hyperplastic/dysplastic islets, to angiogenic islets, to varying grades of solid tumor, with a well-defined angiogenic progression [ 27 ] . All Rip1-Tag2 mice succumb to hypoglycemia and tumor burden by 13-16 weeks.