Words similar to hyperplastic
Example sentences for: hyperplastic
How can you use “hyperplastic” in a sentence? Here are some example sentences to help you improve your vocabulary:
A diffusely hyperplastic lesion with no known neoplastic properties, but with a frequent association with cancer arising from the hyperplastic tissue, would be considered a precancer.
In order to determine if cyclin D 1 plays a role in this hyperplasia, kidneys from three proteinuric 40-day old transgenic siblings and three non-transgenic littermates were stained by immunohistochemistry with antibody to phospho-pRb (Ser780), a site of cyclin D 1 /CDK-4/6 phosphorylation not targeted by cyclin E/CDK-2 complexes that disrupts pRb/E2F binding for G 1 → S progression [ 24 ] . Figure 1depicts the intense, heterogeneous nuclear staining of glomerular podocytes and tubular epithelium from hyperplastic nephrons in the diseased transgenics versus the absent staining of nephrons in the non-transgenics consistent with the very low mitotic index in normal kidneys of adult animals [ 26 ] . This suggests that cyclin D 1 is promoting cell-cycle progression during the proliferation of epithelium in diseased kidneys.
Pten was detected, at reduced levels, in both hyperplastic ducts and mammary tumors that did not have LOH at the Pten allele (Fig.
As expected, phosphorylated AKT was undetectable in hyperplastic ducts, in tumors from Wnt-1 TG, Pten +/+ mice, and tumors from Wnt-1 TG, Pten +/- mice that retained the wild type allele (Fig.
benzene toxicity), where the marrow is repopulated by an emerging population of hyperplastic cells that carry a a heightened risk of progressing to acute leukemia.
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