Words similar to hyperplastic
Example sentences for: hyperplastic
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However, in both intervention and regression trials, significant CD4 +T cell and CD8 +T cell infiltration into hyperplastic/dysplastic islets and tumors was noted in Rip1-Tag2 mice that had received the combination of sub-lethal radiation and adoptive transfer of TCR splenocytes.
The mice show systemic tolerance to Tag, mounting neither humoral nor cellular immune responses to Tag upon immunization of purified protein [ 25 26 ] . Rip1-Tag2 mice display a reproducible pattern of multistage tumor development, from normal islets to hyperplastic/dysplastic islets, to angiogenic islets, to varying grades of solid tumor, with a well-defined angiogenic progression [ 27 ] . All Rip1-Tag2 mice succumb to hypoglycemia and tumor burden by 13-16 weeks.
Frequent allelic loss at chromosomal locations 2q, 3p, 4q, 6p, 6q, 8p, 8q, 9p, 11q, 13q, 14q and 17q is observed in head and neck cancer [ 4 8 9 10 11 ] . Molecular studies of hyperplastic, dysplastic, CIS, and invasive head and neck lesions indicate that loss of heterozygosity at chromosomal locations 3p, 9p and 17p are early events in head and neck carcinogenesis [ 4 12 ] . Specific tumor suppressor genes, such as FHIT (3p14.
Precancers in Inherited hyperplastic syndromes => 25
Several weeks later, a spontaneous autoimmune response to Tag is readily detectable, with significant lymphocyte infiltration of hyperplastic/dysplastic islets.