Example sentences for: hyperplasia

How can you use “hyperplasia” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Results showed that all three cases spanned a morphologic spectrum ranging from columnar cell hyperplasia to ductal carcinoma in situ . Case 1 (columnar cell hyperplasia) contained two ducts of interest lined by about 500 epithelial cells surrounded by morphologically distinct ME cell layers on the H&E-stained section (Fig.

  • The use of new generation laser systems that offer phototherapeutic ablation mode with transition zones are expected to minimize epithelial hyperplasia and corneal stroma healing response.

  • TTP-deficient mice exhibit cachexia, with dermatitis, medullary and extramedullary hyperplasia, erosive polyarthritis, and autoimmunity with autoantibodies [ 25 ] . This phenotype is similar to that observed in mice that overexpress TNF [ 26 ] . In agreement with these data, TTP-deficient mice were shown to overproduce TNF, and weekly injections of a neutralizing antibody to TNF eliminated the predominant features of this phenotype.

  • Cyclin D 1 is characterized as the major D-type cyclin controlling G 1 -phase progression in kidney cells, both during normal and abnormal proliferation [ 22 23 ] . To determine whether cyclin D 1 may be active in promoting G 1 → S progression in kidneys expressing HIV-1 genes, we utilized a well-characterized HIV-1 transgenic mouse model (Tg26) of HIVAN [ 11 12 13 ] . Secondary to renal expression of the HIV-1 NL4-3 Δ gag-pol proviral transgene, adolescent Tg26 transgenics develop a progressive, proliferative renal disease marked by podocyte and tubular epithelial hyperplasia that is indistinguishable both clinically and histopathologically from human HIVAN.

  • A previous study examined the effect of Ad.TGF-β1 in the knee joints of naïve C57/Bl/6 mice where gene transfer of TGF-β1 to the mouse knee resulted in hyperplasia of the synovium as well as in chondro-osteophyte formation at the chondrosynovial junctions [ 10 ] . The present experiments have shown similar effects on synovial proliferation, but also have extended the murine studies to examine the effects of TGF-β1 in both diseased knee joints and normal knee joints in the rabbit.


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