Words similar to hus
Example sentences for: hus
How can you use “hus” in a sentence? Here are some example sentences to help you improve your vocabulary:
Studies suggest that Hus1, Rad1, and Rad9 function together to form a PCNA-like clamp complex that is loaded onto DNA by Rad17 [ 16 ] . This model predicts that all four proteins should show the same levels of TBZ sensitivity since deletion of any of the four proteins should prevent formation of a functional clamp.
HUS is thought to be due, at least in large part, to Shiga toxin (Stx)-mediated cell toxicity [ 4 ] . Since the kidney is a primary target of Stx in patients with HUS, it has been hypothesized that the preferential renal injury occurring in children with HUS is related to heightened renal susceptibility to Stx in this age group.
Confirmation of these observations is needed, however they do suggest that Gb3 levels, and in particular the pattern of renal Gb3 expression, may be a factor in the age-related incidence of renal injury in HUS.
Clinical data indicate that the peak incidence of HUS occurs around two years of age, but the disease clearly occurs in significant numbers of older children [ 1 ] . Population-based studies suggest that there is a decline in the incidence of HUS from a peak at age 1-2 years until a nadir at about age 11 years [ 1 2 ] . In addition, a case-control study of the Washington State outbreak of HUS revealed that the mean age of patients with HUS was 8 years, while the mean age of patients without HUS was 15 years [ 3 ] . These studies raise the possibility, therefore, that the appearance or disappearance of a factor or factors in adolescents and adults reduces susceptibility to end-organ injury in HUS.
The rad26-GFP allele was crossed into five checkpoint radΔ alleles ( hus1Δ , rad1Δ , rad9Δ , rad17Δ and rad3Δ ) and Rad26-GFP localization was assayed in Triton X-100 extracted cells.
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