Words similar to hus
Example sentences for: hus
How can you use “hus” in a sentence? Here are some example sentences to help you improve your vocabulary:
Clinical data indicate that the peak incidence of HUS occurs around two years of age, but the disease clearly occurs in significant numbers of older children [ 1 ] . Population-based studies suggest that there is a decline in the incidence of HUS from a peak at age 1-2 years until a nadir at about age 11 years [ 1 2 ] . In addition, a case-control study of the Washington State outbreak of HUS revealed that the mean age of patients with HUS was 8 years, while the mean age of patients without HUS was 15 years [ 3 ] . These studies raise the possibility, therefore, that the appearance or disappearance of a factor or factors in adolescents and adults reduces susceptibility to end-organ injury in HUS.
The decreased incidence of HUS renal disease in adolescents and adults raises the possibility that factors associated with puberty may be involved.
It is evident that the peak incidence of HUS occurs in very young children (1-2 years of age).
As stated earlier, there is no precedent in the literature for examination of the effect of sex steroids on Stx responsiveness, however, the coincidental fall in clinically apparent HUS in adolescents and adults [ 1 ] raises the possibility that hormonal changes associated with puberty induce a relatively Stx-resistant state in the kidney.
HUS is thought to be due, at least in large part, to Shiga toxin (Stx)-mediated cell toxicity [ 4 ] . Since the kidney is a primary target of Stx in patients with HUS, it has been hypothesized that the preferential renal injury occurring in children with HUS is related to heightened renal susceptibility to Stx in this age group.
Loading...