Words similar to hus
Example sentences for: hus
How can you use “hus” in a sentence? Here are some example sentences to help you improve your vocabulary:
It is evident that the peak incidence of HUS occurs in very young children (1-2 years of age).
The rad26-GFP allele was crossed into five checkpoint radΔ alleles ( hus1Δ , rad1Δ , rad9Δ , rad17Δ and rad3Δ ) and Rad26-GFP localization was assayed in Triton X-100 extracted cells.
Although speculative, it is tempting to propose that HPT and HGEC may be early targets of Stx-1 and that this could play a role in the pathophysiologic processes that characterize renal injury in HUS.
In fission yeast, the checkpoint rad +genes ( hus1 +, rad1 +, rad3 +, rad9 +, rad17 +and rad26 +) and chk1 +manage the sensing and transducing operations of the DNA damage checkpoint [ 1 16 ] . Current data suggest that the Rad26/Rad3-kinase complex initially senses DNA damage by an unknown mechanism [ 17 ] . This response leads to an increase in the kinase activity of the complex [ 18 ] , which phosphorylates and activates the transducing protein kinase, Chk1 [ 19 ] . Finally, Chk1 delays mitotic entry by targeting Cdc25 and Wee1, regulators of cyclin-dependent kinase activity [ 20 21 22 ] .
HUS is thought to be due, at least in large part, to Shiga toxin (Stx)-mediated cell toxicity [ 4 ] . Since the kidney is a primary target of Stx in patients with HUS, it has been hypothesized that the preferential renal injury occurring in children with HUS is related to heightened renal susceptibility to Stx in this age group.
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