Words similar to hus
Example sentences for: hus
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Clinical data indicate that the peak incidence of HUS occurs around two years of age, but the disease clearly occurs in significant numbers of older children [ 1 ] . Population-based studies suggest that there is a decline in the incidence of HUS from a peak at age 1-2 years until a nadir at about age 11 years [ 1 2 ] . In addition, a case-control study of the Washington State outbreak of HUS revealed that the mean age of patients with HUS was 8 years, while the mean age of patients without HUS was 15 years [ 3 ] . These studies raise the possibility, therefore, that the appearance or disappearance of a factor or factors in adolescents and adults reduces susceptibility to end-organ injury in HUS.
As stated earlier, there is no precedent in the literature for examination of the effect of sex steroids on Stx responsiveness, however, the coincidental fall in clinically apparent HUS in adolescents and adults [ 1 ] raises the possibility that hormonal changes associated with puberty induce a relatively Stx-resistant state in the kidney.
Furthermore, these Rad26-GFP localization patterns appeared normal in hus1Δ , rad1Δ , rad9Δ , rad17Δ , and rad3Δ backgrounds.
The spots may form in response to spontaneous DNA damage that can arise during a typical cell cycle, and the absence of Hus1, Rad1, Rad3, Rad9 or Rad17 may increase these events.
Although speculative, it is tempting to propose that HPT and HGEC may be early targets of Stx-1 and that this could play a role in the pathophysiologic processes that characterize renal injury in HUS.