Words similar to hotspot
Example sentences for: hotspot
How can you use “hotspot” in a sentence? Here are some example sentences to help you improve your vocabulary:
Initially, each exon bearing a mutational hotspot was individually PCR amplified in a polyacrylamide gel giving rise to one polymerase colony, or polony, per copy of genomic p53 or K- ras 2 DNA.
For each position within a mutational hotspot to be genotyped, 20 μL of master mix was combined with 1 μL of genomic DNA as well as 0.23 μL of each the forward and reverse primers (50 μM each; see Table 1) designed to polony amplify the portion of the exon bearing the mutational hotspot(s).
Connecting these ideas about the evolution of recombination modifiers to the question of recombination hotspots, we come to the possibility that individual hotspots may have arisen as a byproduct of linkage disequilibrium between genes on either side of the hotspot that were under selection.
All of the peptides were competed by both TNFα and TNFβ implying they recognized a hotspot that mapped either within or at least overlapping the ligand-binding domain of TNFR2.
The HSPLs KcC7, KcD11, KcF6 but not KcF12 were also inhibited by the neutralizing antibody mAb226 suggesting the 20 mers but not KcF12 interact with a hotspot overlapping with the one recognized by antibody.