Example sentences for: hotspot

How can you use “hotspot” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The fact that recombinant KcF12 peptide competed all of the phage expressed peptides (Table 3) indicated that the four peptides also recognize a common hotspot which may be the one responsible for TNF ligand binding to the receptor.

  • For example, sequencing each mutational hotspot is laborious and detecting mutations outside the hotspots is not feasible.

  • This is surprising because these peptides share a hotspot with the natural ligand TNFα (which is proliferative rather than-cytotoxic) and KcC7 and KcF6 bind to a hotspot common to the neutralizing but non-cytotoxic, antibody mAb226.

  • The H2-Eb1 gene contains a recombination hotspot, which has a predominant role in generating different recombinants through meiotic crossing-over within the I region of the mouse major histocompatibility complex (MHC) [ 24].

  • The successful isolation of a useful surrogate may seem an improbable task especially in cases where nothing is known about the hotspot surface(s) on a target.


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