Example sentences for: hotspot

How can you use “hotspot” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Initially, each exon bearing a mutational hotspot was individually PCR amplified in a polyacrylamide gel giving rise to one polymerase colony, or polony, per copy of genomic p53 or K- ras 2 DNA.

  • The successful isolation of a useful surrogate may seem an improbable task especially in cases where nothing is known about the hotspot surface(s) on a target.

  • The first case is illustrated in Figure 4afor E. coli, in which the terminus of replication, which is a recombination hotspot, has no gene order conservation because of the extensive rearrangement in this region.

  • The H2-Eb1 gene contains a recombination hotspot, which has a predominant role in generating different recombinants through meiotic crossing-over within the I region of the mouse major histocompatibility complex (MHC) [ 24].

  • But this krill hotspot is showing some of the most dramatic changes in sea ice extent.


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