Example sentences for: homeodomain

How can you use “homeodomain” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In the case of the POU homeodomain factor Pit-1, transcriptional activity is potentiated by MAPK pathways [ 86 ] . Therefore, down-regulation of MAPK pathway members in Tat expressing cells, as seen in Table 3, is consistent with decreased phosphorylation of DNA binding factors such as Pit-1, and overall lower DNA binding activity.

  • Unlike several DNA-binding domains conserved throughout eukaryotes, such as the homeodomain, the bHLH, bZip, C2H2 zinc finger and the RFX domain, APSES domains are restricted to fungi [ 27, 28].

  • Isl1 is a LIM homeodomain transcription factor expressed in motor neurons and dorsal root and cranial sensory ganglia [ 24].

  • 5 wild-type mice along with littermates mutant for the crx gene (which encodes a Paired type homeodomain transcription factor that directly regulates transcription of many photoreceptor-enriched genes); adult mouse retina; and microdissected outer nuclear layer, which consists entirely of rod and cone photoreceptors [ 11 ] . We examined this very large dataset for expression of genes known to be photoreceptor specific (Figure 2).

  • An important type of transcription factor contains a conserved region of 60 amino acids called the homeodomain (HD), encoded by a DNA region, the homeobox (HB).


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