Words similar to homeodomain

Example sentences for: homeodomain

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Two of these models represent the genes kl-5 and scro , and the region of similarity in scro corresponds to the homeodomain of this transcription factor gene.
5 wild-type mice along with littermates mutant for the crx gene (which encodes a Paired type homeodomain transcription factor that directly regulates transcription of many photoreceptor-enriched genes); adult mouse retina; and microdissected outer nuclear layer, which consists entirely of rod and cone photoreceptors [ 11 ] . We examined this very large dataset for expression of genes known to be photoreceptor specific (Figure 2).
Consistent with this interpretation, we also did not detect expression of homeodomain proteins Hoxc6 or Hoxb9 (see Figure 1B; data not shown), which are induced by RA in spinal cord neuronal precursor cells [21].
Thus far, this phenotype segregates as an autosomal recessive trait and maps to the FEOM2 locus on chromosome 11q13 [ 8 ] , and affected individuals carry homozygous mutations in ARIX [ 5 ] . ARIX encodes a homeodomain transcription factor required for nIII and nIV development in mice and zebrafish [ 22 23 ] . In families with CFEOM3, the CFEOM phenotype is variably expressed.
DCIS = ductal carcinoma in situ ; ER = estrogen receptor; HB = homeobox; HD = homeodomain; PR = progesterone receptor; RT-PCR = reverse transcription polymerase chain reaction.