Example sentences for: homeobox

How can you use “homeobox” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Homeobox genes of the Hox class are required for proper patterning of skeletal elements [ 7 ] . The functional role of Hox genes in skeletal growth and development has been clearly demonstrated, but how they control the differentiation of specific tissues is not well understood.

  • For example, the link between homeobox proteins (PF00046) and other protein families.

  • We have cloned a human homeobox cDNA called BP1, belonging to the DLX family.

  • We found a similar phenotype upon overexpression of Hoxd-4 in our transgenic system (Kappen, manuscript in preparation), whereas overexpression of the LIM-homeodomain transcription factor Isl-1 did not cause abnormalities in cartilage but other developmental defects [ 1 9 ] . The observation that cartilage is affected by misregulation of Hoxc-8 and Hoxd-4, but not by a divergent homeobox gene, indicates that the capacity to regulate cartilage differentiation is specific to homeobox genes of the Hox subclass.

  • An important type of transcription factor contains a conserved region of 60 amino acids called the homeodomain (HD), encoded by a DNA region, the homeobox (HB).


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