Example sentences for: homeostasis

How can you use “homeostasis” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In some differentiating cell types, changes in both gene transcription and proliferation are regulated by the same transcription factor [ 1 2 3 4 5 6 7 8 9 ] . CCAAT/Enhancer Binding Protein alpha (C/EBPα) is a transcription factor that is required for the differentiation of a number of tissues [ 10 11 12 13 14 15 16 17 18 ] . Mice homozygous for C/EBPα null alleles have severe defects in tissues involved in metabolic homeostasis [ 19 20 21 ] . Cellular proliferation is elevated in the liver of these knockout mice [ 22 ] suggesting that C/EBPα blocks proliferation in vivo.

  • Recent work has shown that the Bcl-2 family regulates mitochondrial homeostasis during apoptosis [ 1 ] . Pro-apoptotic members, including Bax, Bak, Bid, and Bim, promote the release of death-inducing proteins, such as cytochrome c [ 2 3 ] , smac [ 4 ] , and endonuclease G [ 5 ] , from mitochondria while anti-apoptotic members, such as Bcl-2 and Bcl-X L , inhibit this release.

  • This skewed differentiation was not observed in healthy age-matched control individuals and in SLE patients, indicating that this perturbation in homeostasis of T cells is a specific feature of RA.

  • The effects of mefloquine on ER calcium homeostasis have been examined previously [ 5 6 ] . In experiments with isolated rabbit skeletal muscle microsomes, mefloquine was found to inhibit the uptake of calcium, with an IC 50 of approximately 43 μM [ 6 ] . This effect was exacerbated by treatment with thapsigargin, a specific inhibitor of the ER calcium pump [ 6 ] . Further, the rate of ATP hydrolysis by the ER Ca 2+-ATPase was reduced in the presence of mefloquine (Ki of = 53 μM).

  • It controls serum tryptophan homeostasis and is induced following ingestion of tryptophan.


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