Words similar to hig-

Example sentences for: hig-

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In our initial experiments we compared the inhibitory activity of rIL-1Ra to that of HIG-82-IL-1Ra +cells - a cell line engineered to constitutively express human IL-1Ra - when each was added to HSF cultures simultaneously with IL-1β.
For the addition of cells, cultures of HIG-82-IL-1Ra +, or dermal fibroblasts secreting IL-1β, were trypsinized, washed in PBS, and resuspended in complete DMEM.
Non-transduced HIG-82 cells used as negative controls were cultured in Ham's F12 medium with 10% FBS and 1% penicillin-streptomycin.
These cells, HIG-82-IL-1Ra +, were found to secrete approximately 3 μg IL-1Ra/ml per 10 6cells over 24 hours.
At the low and medium doses rIL-1Ra had little protective effect but, relative to the 24 hour time point, a significant increase in IL-1 stimulation was seen in the wells receiving the high dose by day 4. In the wells receiving the HIG-82-IL-1Ra +cells, protection from IL-1 stimulation was maintained over time.