Words similar to hic

Example sentences for: hic

How can you use “hic” in a sentence? Here are some example sentences to help you improve your vocabulary:

The HIC1 gene was methylated in 5 of 8 cell lines.
The overall higher frequency of promoter methylation seen in NSGCTs is noticeably evident in DNA repair genes RASSF1A, BRCA1 , and MGMT , and the hypermethylated in cancer 1 ( HIC1 ) gene, which encodes a transcription factor.
2% of CC [ 13 ] . HIC1 is a zinc finger transcription factor that is transcriptionally silenced by promoter methylation in several types of human cancer [ 26 ] . Heterozygous Hic1 mouse with promoter methylation of wild type allele develop carcinomas, sarcomas and lymphomas, suggesting that this gene acts as a tumor suppressor gene [ 27 ] . HIC1 gene was down regulated in majority of the CC cell lines examined by us and this down-regulated expression was reactivated upon treatment with demethylating and HDAC-inhibiting agents.
We found that methylation of HIC1 , APC , and BRACA1 genes was more common in AC while CDH1 promoter methylation was seen only in SCC.
Promoter methylation of the CDH1 , RARB , FHIT , and MGMT genes was noted only in SCC, whereas the AC exhibited significantly higher frequency of promoter methylation of HIC1 (60% in AC vs. 15.