Words similar to hic

Example sentences for: hic

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The relative change was calculated as the absolute change divided by the baseline HIC.
2% of CC [ 13 ] . HIC1 is a zinc finger transcription factor that is transcriptionally silenced by promoter methylation in several types of human cancer [ 26 ] . Heterozygous Hic1 mouse with promoter methylation of wild type allele develop carcinomas, sarcomas and lymphomas, suggesting that this gene acts as a tumor suppressor gene [ 27 ] . HIC1 gene was down regulated in majority of the CC cell lines examined by us and this down-regulated expression was reactivated upon treatment with demethylating and HDAC-inhibiting agents.
This apparent comparability in reduction of HIC is in conflict, however, with the results of another recently published study.
The mean HIC at endpoint, considering all patients, was 14.
To examine the biological role of promoter methylation in CC, we assessed the levels of mRNA by semi-quantitative RT-PCR in eight cell lines and compared with the respective control values obtained from the averages calculated from 2 normal cervix after normalization against ACTB . This analysis was performed on 7 genes ( CDH1 , DAPK , RARB , HIC1 , MGMT , RASSF1A , and MLH1 ) that exhibited methylation in one or more cell lines and primary tumors (Fig.