Words similar to hif-

Example sentences for: hif-

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An inhibitory effect of USF on Myc-mediated cellular proliferation has been demonstrated in HeLa cells [ 33 ] , and a non-canonical HLH element inhibits expression of the fibroblast growth factor binding protein (FGF-BP) in several carcinoma cells [ 34 ] . Furthermore, USF2 inhibits binding of hypoxia-inducible factor-1 (HIF-1) to the plasminogen activator inhibitor -1 (PAI-1) gene in hepatocytes in order to disturb transcriptional activation [ 35 ] . Our results add C/EBPβ-mediated activation of RIIβ to the mechanisms inhibited by USF.
Delivery of intracellular modulators for therapeutic angiogenesis, including transcription factors that control angiogenesis such as hypoxia inducible factor-1 alpha (HIF-1α), is only possible through gene therapy.
However, hypoxia-mediated HIF-1α responses are also linked to the regulation of mitochondrial dysfunction through the formation of excessive reactive oxygen species in mitochondria.
ang = angiopoietin; CEP = circulating endothelial precursor; FGF = fibroblast growth factor; FGF-1 = acidic fibroblast growth factor; FGF-2 = basic fibroblast growth factor; HIF-1α = hypoxia inducible factor-1 alpha; SPECT = single photon emission computed tomography; VEGF = vascular endothelial growth factor.
Another approach that addresses the involvement of multiple factors in therapeutic angiogenesis is the use of a so-called 'master switch gene' of angiogenesis, such as HIF-1α [ 52].