Example sentences for: hif-

How can you use “hif-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Ablation of HIF-1α in skeletal muscle was associated with an increase in the activity of rate-limiting enzymes of the mitochondria, indicating that the citric acid cycle and increased fatty acid oxidation may be compensating for decreased flow through the glycolytic pathway in these animals.

  • ang = angiopoietin; CEP = circulating endothelial precursor; FGF = fibroblast growth factor; FGF-1 = acidic fibroblast growth factor; FGF-2 = basic fibroblast growth factor; HIF-1α = hypoxia inducible factor-1 alpha; SPECT = single photon emission computed tomography; VEGF = vascular endothelial growth factor.

  • However, hypoxia-mediated HIF-1α responses are also linked to the regulation of mitochondrial dysfunction through the formation of excessive reactive oxygen species in mitochondria.

  • 2004), a key role for HIF-1α in mediating exercise-induced gene regulatory responses of glycolytic enzymes is revealed.

  • A subsequent study, demonstrating an age-dependent reduction in HIF-1α activity, provides one explanation for the lower VEGF-A expression in response to hypoxia in aged animals [ 28].


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