Example sentences for: hexameric

How can you use “hexameric” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • At this point, there is about 8.4% of the cell's myosin-II (about 1 × 10 5hexameric monomers) localized to the cleavage furrow cortex.

  • In both midasin and dynein, the evolutionary fusion of the six AAA protomers into a single polypeptide has permitted the individual protomers in the hexameric assembly to acquire substantial structural and functional specialization.

  • In many cases, conformational changes occurring in the individual AAA protomers during an ATPase cycle function cooperatively to change the shape of the overall hexameric ring in a manner that exerts mechanical force on their protein or nucleic acid substrates.

  • These critical residues lie close to the γ-phosphate site in other AAA proteins with known structures and they are believed to trigger a change in the angle between the N- and C-subdomains of the protomer upon binding of ATP or dissociation of the γ-phosphate [ 18 ] . Indirect evidence suggests that such a conformational change in one protomer can be communicated to the adjacent protomers and result in a cooperative alteration in the shape of the overall hexameric ring [ 19 ] .

  • To determine the percentage of total cellular myosin-II, the following assumptions were used to calculate the total amount of myosin-II in a cell: total protein concentration in D. discoideum is 50 μg/10 6cells [ 37 ] , myosin-II represents about 1% of the cell's protein [ 38 39 ] , the relative molecular mass of a hexameric "monomer" (two each of the heavy chain and essential and regulatory light chains) of myosin-II is 557 kDa, and the average size of a D. discoideum cell is about 8 μm in diameter when grown on surfaces.


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