Example sentences for: hexameric

How can you use “hexameric” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In dynein, this has included the acquisition of two substantial accessory structures that protrude asymmetrically from the hexameric AAA ring.

  • In contrast to their shared structure, the AAA proteins participate in diverse cellular activities, including proteolysis, protein folding and unfolding, membrane trafficking, DNA replication, metal ion metabolism and intracellular motility [ 13 14 15 ] . Recent structural studies have revealed that the protomers of an AAA protein usually oligomerize into ring-shaped hexameric structures that constitute molecular platforms essential to their mode of action.

  • To determine the percentage of total cellular myosin-II, the following assumptions were used to calculate the total amount of myosin-II in a cell: total protein concentration in D. discoideum is 50 μg/10 6cells [ 37 ] , myosin-II represents about 1% of the cell's protein [ 38 39 ] , the relative molecular mass of a hexameric "monomer" (two each of the heavy chain and essential and regulatory light chains) of myosin-II is 557 kDa, and the average size of a D. discoideum cell is about 8 μm in diameter when grown on surfaces.

  • At this point, there is about 8.4% of the cell's myosin-II (about 1 × 10 5hexameric monomers) localized to the cleavage furrow cortex.

  • These critical residues lie close to the γ-phosphate site in other AAA proteins with known structures and they are believed to trigger a change in the angle between the N- and C-subdomains of the protomer upon binding of ATP or dissociation of the γ-phosphate [ 18 ] . Indirect evidence suggests that such a conformational change in one protomer can be communicated to the adjacent protomers and result in a cooperative alteration in the shape of the overall hexameric ring [ 19 ] .


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