Words similar to hexameric
Example sentences for: hexameric
How can you use “hexameric” in a sentence? Here are some example sentences to help you improve your vocabulary:
At this point, there is about 8.4% of the cell's myosin-II (about 1 × 10 5hexameric monomers) localized to the cleavage furrow cortex.
However, such primordial di-protomeric AAA polypeptides would have to have been simpler than those present in NSF, ClpA and p97 and other AAA proteins of the current era, for the latter assemble into two-tiered hexameric assemblies, with the axis joining the two protomers in each polypeptide oriented perpendicular to the plane of the hexameric ring [ 14 ] . We cannot, at present, exclude an alternative model for midasin structure in which the hexameric AAA ring assembly is a dimeric two-layered structure formed by two midasin polypeptides arranged laterally with all six odd-numbered protomers in one layer and all six even-numbered protomers in the other.
To determine the percentage of total cellular myosin-II, the following assumptions were used to calculate the total amount of myosin-II in a cell: total protein concentration in D. discoideum is 50 μg/10 6cells [ 37 ] , myosin-II represents about 1% of the cell's protein [ 38 39 ] , the relative molecular mass of a hexameric "monomer" (two each of the heavy chain and essential and regulatory light chains) of myosin-II is 557 kDa, and the average size of a D. discoideum cell is about 8 μm in diameter when grown on surfaces.
The essentially complete retention of the M-domain and the hexameric assembly of protomers in the AAA domain emphasizes the critical importance of these domains to the proper functioning of midasin.
These critical residues lie close to the γ-phosphate site in other AAA proteins with known structures and they are believed to trigger a change in the angle between the N- and C-subdomains of the protomer upon binding of ATP or dissociation of the γ-phosphate [ 18 ] . Indirect evidence suggests that such a conformational change in one protomer can be communicated to the adjacent protomers and result in a cooperative alteration in the shape of the overall hexameric ring [ 19 ] .
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