Example sentences for: hexameric

How can you use “hexameric” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • These critical residues lie close to the γ-phosphate site in other AAA proteins with known structures and they are believed to trigger a change in the angle between the N- and C-subdomains of the protomer upon binding of ATP or dissociation of the γ-phosphate [ 18 ] . Indirect evidence suggests that such a conformational change in one protomer can be communicated to the adjacent protomers and result in a cooperative alteration in the shape of the overall hexameric ring [ 19 ] .

  • In many cases, conformational changes occurring in the individual AAA protomers during an ATPase cycle function cooperatively to change the shape of the overall hexameric ring in a manner that exerts mechanical force on their protein or nucleic acid substrates.

  • In dynein, this has included the acquisition of two substantial accessory structures that protrude asymmetrically from the hexameric AAA ring.

  • At this point, there is about 8.4% of the cell's myosin-II (about 1 × 10 5hexameric monomers) localized to the cleavage furrow cortex.

  • In contrast to their shared structure, the AAA proteins participate in diverse cellular activities, including proteolysis, protein folding and unfolding, membrane trafficking, DNA replication, metal ion metabolism and intracellular motility [ 13 14 15 ] . Recent structural studies have revealed that the protomers of an AAA protein usually oligomerize into ring-shaped hexameric structures that constitute molecular platforms essential to their mode of action.


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