Words similar to herpes
Example sentences for: herpes
How can you use “herpes” in a sentence? Here are some example sentences to help you improve your vocabulary:
Despite advances in antiviral therapy during acute herpes zoster and the more recent introduction of vaccination against varicella zoster, PHN continues to be a significant clinical problem, with 10–20% of patients developing persistent neuropathic pain after acute herpes zoster reactivation.
We have previously characterized clonal mouse astrocyte cell lines, immortalized by transduction of SV40 large T antigen expressed from the MoMuLV LTR [ 6 13 ] . Here, we compare variation in Tag levels in 3 of these lines and 3 additional lines (termed tkT lines), immortalized with Moloney Sarcoma Virus vectors expressing Tag from an internal herpes thymidine kinase (tk) promoter.
The replicative polymerase of herpes simplex virus (HSV) is comprised of catalytic (Pol) and processivity subunits (UL42) [ 9 11 ] . HSV Pol is responsible, in concert with other viral proteins, for regulating the fidelity of DNA replication by selecting the correct nucleotides for incorporation and by proofreading or editing mispaired nucleotides [ 20 ] . The Pol subunit contains intrinsic 3'-5' exonuclease activity [ 14 15 16 ] and the N-terminal region of the polypeptide encoding this function is highly conserved in other polymerases, containing three segments referred to as Exo motifs [ 3 26 ] .
Hsv-TK - Herpes simplex virus thymidine kinase
CMV, a herpes virus, causes chronic asymptomatic infections in immunocompetent individuals, termed latency [ 13 ] . However, in situations of immunocompromise, CMV is reactivated, which in many cases leads to organ failure and death [ 13 ] . Epidemiological reports indicate that chronic CMV infections in humans may play an important role in pathogenesis of vascular diseases such as atherosclerosis [ 14 ] and systemic sclerosis [ 11 12 ] . In addition, a recent report [ 15 ] revealed that SSc autoantibodies bind to CMV late protein UL94 and induce apoptosis in endothelial cells therefore implicating molecular mimicry as a potential mechanism accounting for the link between SSc and CMV.
Loading...