Words similar to herpes
Example sentences for: herpes
How can you use “herpes” in a sentence? Here are some example sentences to help you improve your vocabulary:
Cell lines were created by incorporation of retroviral vectors into the genome and expression of Tag from either the retroviral LTR (considered to be a strong promoter) or the herpes virus thymidine kinase promoter, internal to the viral LTR [ 1 ] . In our established NIH 3T3 cell line, Tag is expressed from the htk promoter at considerably lower levels than from the LTR for a considerable time after transduction [unpublished observations, and [ 11 ] ]. However, when a large number of htk-Tag astrocyte clones were checked 100 days after creation, the expression levels displayed a very large range, and thus we expect that this weak promoter is subject to positional effects on transcription or mutational events that affect gene expression (unpublished data).
For instance, viruses including Herpes simplex virus type 1 (HSV-1) have been known to induce severe alterations of the host translational apparatus, including the up-regulation of ribosomal proteins and the progressive association of several nonribosomal proteins, such as VP19C, VP26, and the poly(A)-binding protein 1 (PAB1P) to ribosomes [ 39 ] . In the case of HIV-1, approximately one infectious HIV-1 genome in an infected cell could be transcribed and translated into 50,000 to 100,000 physical particles [ 40 ] . This poses an immense challenge for the virus to be able to transcribe, splice, transport, and translate its RNA into fully packaged virions in a timely fashion.
CMV, a herpes virus, causes chronic asymptomatic infections in immunocompetent individuals, termed latency [ 13 ] . However, in situations of immunocompromise, CMV is reactivated, which in many cases leads to organ failure and death [ 13 ] . Epidemiological reports indicate that chronic CMV infections in humans may play an important role in pathogenesis of vascular diseases such as atherosclerosis [ 14 ] and systemic sclerosis [ 11 12 ] . In addition, a recent report [ 15 ] revealed that SSc autoantibodies bind to CMV late protein UL94 and induce apoptosis in endothelial cells therefore implicating molecular mimicry as a potential mechanism accounting for the link between SSc and CMV.
Viral infections were detected in the BAL in 13 hospital admissions among 13 different patients: CMV in 10, respiratory syncytial virus in 1, herpes simplex virus in 1, and influenza B virus in 1. Of the 13 hospital admissions with viral infection, only 1 patient, who had CMV, died.
In the last few years, compelling research has been published about a new, AIDS-related virus named Human Herpes Virus 6 that suggests this virus may be more important in causing immune collapse in AIDS than HIV is.
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