Example sentences for: heptad

How can you use “heptad” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The principal changes are the substitution of either tyrosine or phenylalanine for leucine at the beginning of the third heptad repeat and the addition of a second proline adjacent to the first in the second heptad repeat.

  • The binding site consists of four highly conserved contiguous heptad repeats which are predicted to form a tight α-helical coiled-coil interaction with the heptad repeat-containing N-terminus of the light chain.

  • Because of the long stretches of conserved heptad repeats, BLAST searches with large coiled-coil proteins usually produce significant e-values with at least some of the large number of myosin heavy-chain sequences in GenBank, frequently leading to this annotation.

  • The first class is comprised of short coiled-coil domains of six or seven heptad repeats, also called leucine zippers.

  • Coiled-coil domains are protein oligomerization motifs, which consist of two or more alpha helices that twist around one another to form a supercoil [ 1 ] . Peptides with the capacity to form coiled coils are characterized by a heptad repeat pattern in which residues in the first and fourth position are hydrophobic, and residues in the fifth and seventh position are predominantly charged or polar.


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