Example sentences for: heptad

How can you use “heptad” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Because of the long stretches of conserved heptad repeats, BLAST searches with large coiled-coil proteins usually produce significant e-values with at least some of the large number of myosin heavy-chain sequences in GenBank, frequently leading to this annotation.

  • The outer surface of the coiled-coil contains grooves into which three heptad repeat regions from the C-terminal part of the gp41 ectodomain pack, resulting in a stable six-helix bundle [ 42 45 46 47 48 49 50 51 52 53 54 ] . The six-helix bundle structure can be detected by specific antibodies [ 14 20 43 55 ] .

  • The absence of any consistent pattern of heptad hydrophobic repeats indicates that there is little or no α-helical coiled-coil structure in the domain.

  • The binding site consists of four highly conserved contiguous heptad repeats which are predicted to form a tight α-helical coiled-coil interaction with the heptad repeat-containing N-terminus of the light chain.

  • Coiled-coil domains are protein oligomerization motifs, which consist of two or more alpha helices that twist around one another to form a supercoil [ 1 ] . Peptides with the capacity to form coiled coils are characterized by a heptad repeat pattern in which residues in the first and fourth position are hydrophobic, and residues in the fifth and seventh position are predominantly charged or polar.


How many words do you know? Try our free vocabulary size test!


Search

Search for example sentences

Loading Loading...
Quantcast