Words similar to heptamer

Example sentences for: heptamer

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These are the spacer, especially the nonamer-proximal half, and the positions of the heptamer and nonamer that are adjacent to the spacer (Figure 1b).
With respect to the heptamer (canonical sequence: CACAGTG), the CAC sequence bordering the recombination site is the most conserved segment of the sequence [ 32 ] , and mutation of these nucleotides has been found to decrease V(D)J joining in transfection assays using recombination substrates [ 40 ] . Because the sequence of the canonical RSS heptamer is palindrome, we speculate that the TGTG sequence may be sufficient for KRC/ZAS-C binding.
Using the ZAS-N- and ZAS-C-selected DNA sequences as input, the MEME program discovered motifs containing sequences similar to the κB or Sb transcriptional enhancer motifs as well as the conserved heptamer or nonamer elements of the RSS.
Because the pentameric motifs derived from the KRC/ZAS-N dataset more closely resemble the canonical RSS nonamer and the motif derived from the KRC/ZAS-C dataset more closely resemble the canonical RSS heptamer and a canonical sequence was derived from the majority of sequences, we propose that the ZAS-N domain of KRC binds RSS nonamers more frequently than the ZAS-C domain, and vice versa for the RSS heptamer in vivo .
Since the RSS heptamer is a palindrome, it is possible for two KRC molecules to bind to an RSS heptamer, with one ZAS-C binding to the top strand and the other ZAS-C binding to the bottom strand.