Example sentences for: hepatotoxic

How can you use “hepatotoxic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • However, given that most patients had persistent rather than intermittent abnormalities of LFTs and that the use of hepatotoxic drugs was not elicited in the majority of patients with liver abnormalities, a toxic effect of medications could not be established.

  • The phenomenology of mefloquine's adverse effect profile, together with incidental details in some of the published case reports (references to alcohol, and to known hepatotoxic co-medications such as the oral contraceptive pill) suggest that for many mefloquine users adverse drug effects may be the result of primary hepatocellular injury, caused by the drug in association with one or more concurrent liver insults.

  • Some studies have suggested that excessive amino acids, hepatotoxic bile acids, bacterial overgrowth, sepsis, micronutrient deficiency, and TPN contaminants all contribute to cholestatic liver injury [ 4, 5, 6].

  • For example, lack of enteral feeding plays an important role in the development of cholestasis in the neonatal period, possibly mediated by direct hepatotoxic activity of bile salts [ 5].

  • The multicentre cohort study of prophylactic mefloquine use should be questionnaire-based, and should enquire specifically into the major risk factors (alcohol intake during travel, hydration status, use of hormonal contraception and recreational drugs, other potentially hepatotoxic or thyrotoxic drugs, previous history of proven or suspected liver and/or thyroid abnormality) that we have proposed.


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