Example sentences for: guanylyltransferase

How can you use “guanylyltransferase” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The cap is formed by three enzymatic reactions: the 5' triphosphate end of the nascent pre-mRNA is hydrolyzed to a diphosphate by RNA triphosphatase; the diphosphate end is capped with GMP by RNA guanylyltransferase; and the GpppN cap is methylated by RNA (guanine-7-) methyltransferase [ 1 ] .

  • The group with the largest number of MGI genes in MGI-TC associations included six eosinophil-associated ribonuclease ( Ear1, Ear2, Ear3, Ear8, Ear9 and Ear10 ) and RNA guanylyltransferase and 5'-phosphatase ( Rngtt ) and four TCs (TC561767, TC569331, TC557280 and TC557281).

  • The triphosphatase (Cet1), guanylyltransferase (Ceg1), and methyltransferase (Abd1) components of the capping apparatus are essential for cell growth in the budding yeast S. cerevisiae [ 1 4 5 6 ] . Mutations of the RNA triphosphatase Cet1 that abrogate catalytic activity in vitro are lethal in vivo [ 7 8 9 ] ; thus, it is reasonable to think that pharmacological inhibition of Cet1 function in vivo would impede cell growth.

  • We conclude that the RNA triphosphatase and RNA guanylyltransferase genes are essential for cell growth in S. pombe.

  • S. pombe RNA triphosphatase Pct1 is a 303-amino acid polypeptide with a homodimeric quaternary structure [ 12 ] . The pct1 +gene contains a single intron within the open reading frame [ 12 ] . S. pombe RNA guanylyltransferase Pce1 is a 402-amino acid monomeric protein [ 20 ] ; there are no introns within the pce1 +gene.


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