Words similar to guanylyltransferase
Example sentences for: guanylyltransferase
How can you use “guanylyltransferase” in a sentence? Here are some example sentences to help you improve your vocabulary:
The cap is formed by three enzymatic reactions: the 5' triphosphate end of the nascent pre-mRNA is hydrolyzed to a diphosphate by RNA triphosphatase; the diphosphate end is capped with GMP by RNA guanylyltransferase; and the GpppN cap is methylated by RNA (guanine-7-) methyltransferase [ 1 ] .
The group with the largest number of MGI genes in MGI-TC associations included six eosinophil-associated ribonuclease ( Ear1, Ear2, Ear3, Ear8, Ear9 and Ear10 ) and RNA guanylyltransferase and 5'-phosphatase ( Rngtt ) and four TCs (TC561767, TC569331, TC557280 and TC557281).
The triphosphatase (Cet1), guanylyltransferase (Ceg1), and methyltransferase (Abd1) components of the capping apparatus are essential for cell growth in the budding yeast S. cerevisiae [ 1 4 5 6 ] . Mutations of the RNA triphosphatase Cet1 that abrogate catalytic activity in vitro are lethal in vivo [ 7 8 9 ] ; thus, it is reasonable to think that pharmacological inhibition of Cet1 function in vivo would impede cell growth.
We conclude that the RNA triphosphatase and RNA guanylyltransferase genes are essential for cell growth in S. pombe.
S. pombe RNA triphosphatase Pct1 is a 303-amino acid polypeptide with a homodimeric quaternary structure [ 12 ] . The pct1 +gene contains a single intron within the open reading frame [ 12 ] . S. pombe RNA guanylyltransferase Pce1 is a 402-amino acid monomeric protein [ 20 ] ; there are no introns within the pce1 +gene.
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