Words similar to guanine-nucleotides

Example sentences for: guanine-nucleotides

How can you use “guanine-nucleotides” in a sentence? Here are some example sentences to help you improve your vocabulary:

A recent study identified a number of α5 helix residues in α t that when changed to alanines increased rates of guanine-nucleotide exchange ( i.e., decreased affinity for guanine-nucleotides) [ 5 ] . Individual mutation of amino acids in α t , cognate to T330, N332, V333, F337 in α i2 (Figure 1), increased nucleotide exchange rates [ 5 ] . Two of these critical amino acids, N332 and V333 in α i2 , are in fact the first two amino acids that are replaced by the novel splicing in sα i2 (Figure 1).
Several studies have shown that deletions or amino acid substitutions in the extreme C-terminal region of Gα creates a protein defective in guanine-nucleotide binding [ 5 6 7 8 9 10 ] . Rapid release of guanine-nucleotides can result in an unstable Gα [ 9 10 ] . This leads to the prediction that sα i2 is also unstable due to a disruption in the structure of its C-terminus caused by the novel splice sequence.
A number of reports have demonstrated that disruptions in the C-termini of Gα cause reduced affinity for guanine-nucleotides and protein instability.