Example sentences for: glucocorticoids

How can you use “glucocorticoids” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • However, later in the mid-1980s, pharmacological doses of glucocorticoids for the treatment of sepsis were investigated extensively until several clinical trials gave negative results [ 10, 11, 12].

  • Glucocorticoids influence a wide spectrum of cellular functions through their action on soluble intracellular receptors.

  • Heterogeneous groups of medications that have unclear mechanisms of action, but uncontested benefits in some patients include glucocorticoids (eg, dexamethasone), cannabinoids (eg, tetrahydrocannabinol), and benzodiazepines (eg, lorazepam) [ 61 62 63 ] .

  • Glucocorticoids (CORT) function through the GR to both activate specific gene expression as well as transrepress NF-κB [ 41 ] . Since GR confers this latter effect by associating through protein-protein interactions with NF-κB bound at κB response elements [ 43 44 45 46 47 ] , it is important to also evaluate changes in GR protein levels (see below).

  • Glucocorticoids have been shown in various studies to inhibit DNA synthesis [ 13 14 15 ] . Therefore, we hypothesized that blocking the glucocorticoid receptor by the potent antagonist RU 486 would result in increased incorporation of BrDU into hepatocyte DNA, indicating an enhanced cellular proliferative capability.


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