Example sentences for: gluconeogenesis

How can you use “gluconeogenesis” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Phosphoenolpyruvate carboxykinase (Pck1) is the rate-limiting enzyme of gluconeogenesis, and most of its activity is regulated transcriptionally.

  • G6pc converts glucose-6 phosphate to free glucose during gluconeogenesis.

  • As insulin resistance and gluconeogenesis increase during surgery-related stress and anesthesia, additional insulin will be needed to prevent excessive hepatic glucose release.

  • Overall, LC-PUFA may up regulate Pck1, the rate-limiting enzyme in gluconeogenesis, via cAMP-, SREBP-1- and/or PPAR-signaling [ 57 ] . This has the overall effect of limiting fat accumulation and shunting metabolic flux to gluconeogenesis.

  • Numerous hepatic genes containing SRE promoters were regulated by LC-PUFA in the present experiments, including SREBP-1 itself (consistent with [ 35 36 ] ). Also regulated were genes involved in triacylglycerol synthesis (Gpam), FA synthesis and elongation (Acas1, Acly, FA synthase, Spot14, Elovl2; Elovl2 may speculatively contain an SRE as described by Moon and colleagues [ 35 ] ), FA desaturation (Scd1), gluconeogenesis (Pck1), cytochrome p450 metabolism (Cyp4a-10 and -14), FA transport (Cd36), cholesterol metabolism and transport (Fpps), and ketone body formation (mitochondrial Hmgcs2).


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