Words similar to glucocorticoid
Example sentences for: glucocorticoid
How can you use “glucocorticoid” in a sentence? Here are some example sentences to help you improve your vocabulary:
However, these responses to adrenalectomy failed to reduce food intake, body weight, adiposity, or leptin in mice made obese by the high-fat diet, in which the obsese state was not associated with elevated glucocorticoid levels.
On the other hand, obesity in humans does not generally entail elevated plasma cortisol [ 9 10 11 12 13 ] and it is not clear how effective reduction of glucocorticoid production would be to reverse obesity if glucocorticoid production were otherwise normal.
In most cells, unliganded glucocorticoid receptors (GR) reside predominately in the cytoplasm, where they exist as a heteromeric complex comprised minimally of GR, 90-kDa and 70-kDa heat shock proteins (hsp90 and hsp70).
IL-8, MCP-1 and RANTES gene expression are regulated by the redox responsive transcription factor NF-κB [ 18 20 23 25 26 27 28 29 30 31 32 33 41 42 43 44 ] . The NF-κB signaling pathways have been shown to be differentially affected by antioxidants and glucocorticoid steroids [ 45 ] . To determine whether RSV and TNFα induction of chemokine expression might be mediated by different NF-κB signaling pathways we pretreated A549 cells with the glutathione precursor N-acetyl-L-cysteine (NAC) or the synthetic glucocorticoid dexamethasone (DEX).
NF-κB and the glucocorticoid receptor
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