Words similar to glucocorticoid

Example sentences for: glucocorticoid

How can you use “glucocorticoid” in a sentence? Here are some example sentences to help you improve your vocabulary:

Rab24(D123I) disrupts nuclear import of glucocorticoid receptor
In most cells, unliganded glucocorticoid receptors (GR) reside predominately in the cytoplasm, where they exist as a heteromeric complex comprised minimally of GR, 90-kDa and 70-kDa heat shock proteins (hsp90 and hsp70).
The inclusions bear a superficial resemblance to those described in some of the polyglutamine disorders, and appear to sequester Hsp70, ubiquitin, importin-β, and glucocorticoid receptor.
This hypothesis is particularly compelling since recent data suggest that aberrant glucocorticoid activity may play a key role in the development of the metabolic syndrome [ 10 ] .
Chronically elevated cortisol levels caused by Cushing's syndrome leads to central obesity [ 1 ] while the reduction of cortisol caused by Addison's disease leads to decreased body weight [ 2 ] . Obesity in several rodent models is also associated with elevated corticosterone levels, and adrenalectomy reverses some of the phenotypes associated with these forms of obesity [ 3 4 5 6 7 ] . Furthermore, elevated corticosterone production can cause a metabolic syndrome [ 8 ] . These data suggest that reduction of glucocorticoid production might therefore constitute a plausible clinical strategy to treat obesity.