Words similar to gcn

Example sentences for: gcn

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The mutagenized residues probably are indeed important for the function of this protein, but not because they are part of a GCN5-like acetyltransferase domain, which this protein does not contain.
GCN2 of yeast and mammals is a known sensor of amino acid starvation and regulates cellular responses to such starvation [ 24 25 ] . Using degenerate primers and PCR and database searching identified two GCN2-like genes in Dictyostelium , ifkA and ifkB . Thinking that one or both of these genes may play a role in sensing amino acid starvation and in initiating development, we carried out the work described herein to examine their functions.
Using the yeast GCN2 amino acid sequence as a query sequence, searches of the Dictyostelium genomic and cDNA sequence databases revealed two ORFs with significant identity to GCN2 proteins of yeast and mammals.
GCN5-like HATs, which modulate chromatin-associated transcription, belong to a vast superfamily of amino-group acetyl- and myristoyl-transferases with extremely diverse functions [ 37].
In contrast, IfkB begins at the kinase domain and is the only known GCN2-like protein that does not possess a pseudokinase domain.