Words similar to gcn

Example sentences for: gcn

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A hallmark of mRNAs, including the yeast GCN4 mRNA, that are specifically regulated by GCN2 of yeast and mammals is the presence of several uORFs within the 5' UTR [ 24 25 ] . The uORFs of countin mRNA, along with those of yeast GCN2 mRNA, are shown schematically in fig.
GCN5-like HATs, which modulate chromatin-associated transcription, belong to a vast superfamily of amino-group acetyl- and myristoyl-transferases with extremely diverse functions [ 37].
This is similar to the enhanced translation of certain yeast and mammalian mRNAs (GCN4, ATF4, both transcription factors regulated by GCN2) when GCN2 in these organisms is activated by amino acid starvation, even though bulk mRNA undergoes a decrease in translation efficiency [ 24 25 ] . The hallmark of mRNAs that are upregulated by GCN2 and eIF2α phosphorylation is the presence of several upstream open reading frames within their 5' UTRs.
We reasoned that a GCN2-like protein might be involved in sensing amino acid starvation in Dictyostelium and in regulating the growth to development transition.
The two Ifk proteins possess all of the hallmarks of typical GCN2 proteins, including the characteristic kinase domain and the HisRS domain.