Words similar to gcn

Example sentences for: gcn

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A significant difference between the Ifk kinase domain and yeast GCN2 kinase domain is the length of the insert sequence between subdomain IV and V, which is around 290 amino acids in the Dictyostelium Ifk protein and 110 amino acids in yeast GCN2.
Initial studies identified a portion of the ifkB gene using degenerate PCR procedures based on the shared sequences of yeast, Drosophila , and mammalian GCN2 proteins.
We reasoned that a GCN2-like protein might be involved in sensing amino acid starvation in Dictyostelium and in regulating the growth to development transition.
The sequence identity within the HisRS domain of IfkA/B and yeast GCN2 is 28%, with strong conservation within the M1, M2, and M3 motifs that are characteristic of class II aminoacyl-tRNA synthetases [ 37 ] . The similarity between the kinase domains is much higher, with IfkA/B possessing 44% identity with yeast GCN2, with high conservation of all of the kinase subdomains.
Two GCN2-like genes were identified and named ifkA (NCBI accession AAM43647) and ifkB (NCBI accession AAM33717).