Words similar to gcn

Example sentences for: gcn

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Within the amino terminal sequences, yeast and other GCN2 proteins have a degenerate kinase domain of unknown function [ 31 ] . There is a 63 amino acid long sequence in IfkA that has 38% identity to the V and VI subdomains of the IfkA/B kinase domain, indicating the presence of an amino terminal pseudokinase domain in the Dictyostelium protein (fig.
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The mutagenized residues probably are indeed important for the function of this protein, but not because they are part of a GCN5-like acetyltransferase domain, which this protein does not contain.
Although the overall rate of initiation of translation is reduced by eIF2α phosphorylation, the translation of some specific mRNAs is greatly enhanced under these conditions [ 24 25 ] . The characteristic feature of mRNAs whose translation is enhanced by GCN2 phosphorylating eIF2α are several upstream open reading frames (uORF) within the 5' untranslated region (5'UTR) of the mRNAs.
Initial studies identified a portion of the ifkB gene using degenerate PCR procedures based on the shared sequences of yeast, Drosophila , and mammalian GCN2 proteins.