Example sentences for: gastrulation

How can you use “gastrulation” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • As gastrulation starts, the Spemann–Mangold organizer, which includes mostly axial mesodermal precursors, was classically believed to instruct naïve ectoderm to convert to neural tissue.

  • When examining the in vivo effects of HIV-1 Tat protein in the Xenopus embryo, it was found that upon injection of synthetic Tat mRNA into zygotes, a marked delay in gastrulation occurred.

  • SL-1 induction in p2S cells, an untransformed mouse mammary epithelial cell line, triggered the disappearance of E-cadherin and beta-catenin from cell-cell junctions and reduced the expression of beta-catenin [ 35 ] . Wnt-5a and SL-1 may play similar roles in inhibiting cadherin-mediated cell-adhesion, as Wnt-5a decreases Ca 2+-dependent cell adhesion similar to a dominant negative cadherin [ 11 ] . The regulation of SL-1 by Wnt-5a may be important in developmental processes such as gastrulation where Wnt-5a affects the morphogenetic movement of tissues [ 45 ] .

  • Recent work on neural induction comes to two major conclusions: (i) the fibroblast growth factor (FGF) signaling pathway plays a major role in this process, and (ii) neural specification starts well before gastrulation and thus before the formation and function of the organizer.

  • Mechanistically, HIV-1 Tat elicited a general suppression of gene expression, including that of Xbra and gsc , two early genes whose expression are required for proper gastrulation [ 17 ] .


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