Words similar to fibrinogen-binding
Example sentences for: fibrinogen-binding
How can you use “fibrinogen-binding” in a sentence? Here are some example sentences to help you improve your vocabulary:
The kidney-recovered mutant not only recovered fibrinogen binding potential, that was lost when the sagA/pel gene was inactivated, but also the level of fibrinogen-binding exceeded that of the wild type isolate (Fig.
Expression of surface fibrinogen-binding M and M-related proteins was monitored by the ability of intact bacteria to bind radiolabeled fibrinogen.
The mouse selection process results not only in the restoration of a β-hemolytic positive phenotype, but also restored some, but not all, of the phenotypes known to be regulated by sagA/pel [ 4 ] . For example, fibrinogen-binding M and M-related protein expression was restored; however secretion of the cysteine protease, SpeB, or SK was not.
Binding involves a family of adhesins that interact with extracellular matrix components, and these adhesins have been termed microbial surface components recognizing adhesive matrix molecules (MSCRAMMs) [ 1 ] . Specific MSCRAMMs are responsible for localization of S. aureus to particular tissues, and include fibronectin-binding proteins (FnBPs) [ 2 3 ] , fibrinogen-binding proteins [ 4 5 6 ] , elastin-binding adhesin [ 7 ] collagen-binding adhesion [ 8 ] , and a broad-specificity adhesin (MAP) that facilitates low-affinity binding of S. aureus to several proteins, including osteopontin, collagen, bone sialoprotein, fibronectin, fibrinogen, and vitronectin [ 9 ] . S. aureus can utilize MSCRAMMs to adhere directly to cells or can attach to cells through the use of bridging ligands such as Hsp60 which has an affinity for both MSCRAMMs and the β 1 -integrin host cell receptor [ 10 11 ] . Interaction of S. aureus with host cells via MSCRAMMs can induce signal transduction, tyrosine kinase activity, and cytoskeletal rearrangement [ 12 ] .
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