Words similar to fhit

Example sentences for: fhit

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Here we discover a requirement of adenine biosynthesis for high-level dinucleoside polyphosphate accumulation in the absence of the Fhit homolog in S. cerevisiae . By constructing active site mutants of Hnt2 that were expressed in yeast, we demonstrate that ApppN and, to a lesser degree, AppppN levels are controlled by the Hnt2 active site.
Promoter methylation of the CDH1 , RARB , FHIT , and MGMT genes was noted only in SCC, whereas the AC exhibited significantly higher frequency of promoter methylation of HIC1 (60% in AC vs. 15.
On the basis of mutagenesis of the conserved His residues in Fhit [ 39] and the location of these His residues in crystal structures of Hint and Fhit [ 25, 35], a catalytic role was proposed for His114 [ 24].
We presume that compounds 6b , 12b and 13b with 2, 3 or 4 identical CH 2 -phosphorothioadenosyl groups can present a manganese bound 6b -like complex to Fhit in a similar manner.
2%; FHIT , 11.