Example sentences for: fgfr

How can you use “fgfr” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The PTK XXII (nematode kin15/16 related kinases) subfamily was not identified in the human genome, although members of the PDGFR and FGFR branches are about 30-35% identical to known nematode PTK XXII subfamily members.

  • The FGFR1 gene is expressed in myocytes in their terminal differentiation phase.

  • It has been shown that the differentiation of pillar cells depends on activation of Fgfr3 [ 26 ] by FGF's, probably Fgf8, a factor produced by developing and mature inner hair cells [ 18 27 ] . The formation of supporting cells also appears to depend on the proper expression of various bHLH factors such as Hes 1 and 5 which appear to be regulated by the Notch signaling pathway [ 17 28 29 ] . It is possible that the apparent inability of fibers to extend along outer hair cells is related to the lack of differentiation of supporting cells in the absence of mature hair cells.

  • The proximal 5' flank of the FGFR1 gene has a similar clustering of SP-1, Mef2, and SRF sites [ 36 ] . The FGFR1 gene is expressed in terminally differentiated muscle, although at a lower level than in proliferating myoblasts [ 36 ] . The expression depends on Sp-1 sites in the proximal promoter and the binding of Sp-1 and Sp-3 to these sites.

  • However, the similarity of its 5' flank with that of the FGFR1 gene is striking.


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