Words similar to fgf
Example sentences for: fgf
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In transfection assays, full-length constructs of three splice variants of an endogenous coding transcript containing regions antisense to the FGF2 (fibroblast growth factor-2) mRNA can each suppress protein levels (but not mRNA levels) of FGF2 [ 7].
It has been shown that the differentiation of pillar cells depends on activation of Fgfr3 [ 26 ] by FGF's, probably Fgf8, a factor produced by developing and mature inner hair cells [ 18 27 ] . The formation of supporting cells also appears to depend on the proper expression of various bHLH factors such as Hes 1 and 5 which appear to be regulated by the Notch signaling pathway [ 17 28 29 ] . It is possible that the apparent inability of fibers to extend along outer hair cells is related to the lack of differentiation of supporting cells in the absence of mature hair cells.
The fibroblast growth factor (FGF) family consists of an ever-increasing number of peptide growth factors with diverse cellular targets and biological effects [ 1].
Four of the seven known SLC4A genes were found near either an EGF gene or an FGF gene, or both.
Here, the FGF signal leads to neural induction through the coordinated activation of two transcription factors, Ets1/2 and GATAa, whereas FGF does not activate GATAa during its function in mesoderm formation.