Example sentences for: ets

How can you use “ets” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Ese-1/Esx is a member of the Ets transcription factor family and is expressed mainly in epithelial tissue [ 30 ] . Its expression has been detected during mammary gland development and breast tumorigenesis [ 47 48 ] . It is noteworthy that Ese-1/Esx is a potential transcriptional regulator of the TGFβ type II receptor [ 31 ] and overexpression of Ese-1/Esx in non-invasive cells leads to a reduction in cell growth in the presence of TGFβ, presumably because of an increased TGFβ type II receptor level [ 49 ] . It is interesting that TGFβ-dependent downregulation of Ese-1/Esx is not affected by SB-203580.

  • We investigated three potential transcription factor binding sites (CCAAT, κE2, and Ets) within the 43 bp regulatory promoter region and showed that only the Ets binding site influences CD5 expression in EL4 T cells.

  • Transcription factor genes that were modulated by IL-1β included members from the NF-κB family (relB, p100/p52, p105/p50, IκB-ε, c-rel, and p65), the AP-1 family (fra-1 and junB), and the ETS family (ets-1).

  • Further, we showed that the Ets-1 protein binds to the Ets site and that overexpression of Ets-1 leads to increased promoter activity.

  • Perhaps the functional transcriptional complex is determined by induced expression and activation of AP-1 accessory proteins, such as the Fos family member Fra-1, or the ets family member ets-1 [ 31].


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