Words similar to ets
Example sentences for: ets
How can you use “ets” in a sentence? Here are some example sentences to help you improve your vocabulary:
This complex is easily competed away by increasing amount of unlabeled Ets oligos (figure 3, lanes 4 and 5) but not by increasing amounts of irrelevant κE2 oligos (figure 3, lanes 6 and 7).
The other ets gene that we tested was ese-1/esx , a recently characterized member of the ets gene family, originally identified in epithelial cells [ 30 ] . Ese-1/Esx has been found to regulate the expression of TGFβ type II receptor [ 31 ] . We could show for the first time that the level of the Ese-1/Esx transcript was strongly downregulated in the presence of TGFβ.
AP-1 = activator protein-1; COL2A1 = procollagen 2 alpha 1; egr-1 = early growth response gene-1; ets = erythroblastosis gene twenty-six; IL-1β = interleukin-1β; LH = lactalbumin hydrolysate; LIF = leukemia inhibitory factor; MAPK= mitogen-activated protein kinase; MMP = matrix metalloproteinase; NF-κB = nuclear factor-κB; OA = osteoarthritis; PDGF = platelet-derived growth factor; RT-PCR = reverse transcriptase polymerase chain reaction; SMAD4 = mothers against dpp homolog 4; TGF-β = transforming growth factor-β.
The double stranded oligos used were as follows: for the Ets binding site on the CD5 promoter, 5' CGC GTA CAG GGA GGA AGT TGA CCT CGA 3'; for the oligonucleotides containing the CD5X region, 5' AGG CCT AAG TTG ACA GTT CAA CTT CAA ACA CTC GAG 3'; and for the CD5Y oligo, 5' AGG CCT CAC AGG CCC ACA CTG CCT GCT TCC CTG GAG 3'.
We investigated three potential transcription factor binding sites (CCAAT, κE2, and Ets) within the 43 bp regulatory promoter region and showed that only the Ets binding site influences CD5 expression in EL4 T cells.
Loading...