Example sentences for: etorphine

How can you use “etorphine” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The rank order of efficacy of the ligands tested were fentanyl = hydromorphone = β-endorphin > etorphine = lofentanil = butorphanol = morphine= nalbuphine = nalorphine > cyclazocine = dezocine = metazocine ≥ xorphanol.

  • For example, as reported, etorphine [ 19 ] and lofentanil [ 20 ] were shown to be highly potent and efficacious at δ opioid receptors.

  • Louis, MO), nalbuphine and β-endorphin were obtained from RBI (Natik, MA), cyclazocine, etorphine, metazocine, morphine, nalorphine, and SKF 10047 were obtained from National Institute of Drug Abuse (Bethesda, MD), lofentanil was from Janssen Pharmaceutical Inc. (Titusville, NJ), Dezocine was from Wyeth Laboratories (Philadelphia, PA), Win 444,441 was from Sterling Winthrop Pharmaceutical and Xorphanol was from Miles Inc.

  • The IC 50 of all ligands studied were between 1-10 nM, with the exception of etorphine, which was the most potent drug, with an IC 50 of 0.3 nM, morphine, which was the least potent drug with an IC 50 of 12 nM and the endogenous ligand β-endorphin with IC 50 of 500 nM.

  • Antagonists were identified as ligands that were able to repeatedly block the inhibitory effect of 1 nM etorphine on forskolin stimulated cAMP production.


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