Words similar to etn
Example sentences for: etn
How can you use “etn” in a sentence? Here are some example sentences to help you improve your vocabulary:
They showed that the splice site at the 3' end of exon 7 was mutated from TAG GTATGT to TAG GTGTTG (where underlined sequence is the 3' end of exon 7 and ETn insertion sequence is in bold) and predicted that this site would be nonfunctional, thereby abolishing splicing of exon 7 to exon 8. They proposed that the T Wis allele would produce a transcript comprised of exons 1 through 7 followed by read-through transcription of the ETn element, resulting in a modified C-terminal end, or alternatively, that upstream splice donor sites would be used, shortening the transcript and protein product.
A straightforward prediction suggests that in T Wis transcripts, splicing "out of" exon 7 would simply fail and result in a transcript terminating with the ETn element.
As a first step in characterizing the molecular nature of the T Wis allele of T , the exact identity of the ETn element inserted into the locus was determined.
The ETn elements used to design the Etn1 primer were Genbank #s Y17106, Y17107, and X15598.
The longer variant contained the intact 3' end of exon 7 and 60 nt of read-through into the ETn element spliced to a 37 nt mini-exon of ETn sequence, then spliced to exon 8 (7+60ETn,+37ETn,8).