Words similar to er-induced
Example sentences for: er-induced
How can you use “er-induced” in a sentence? Here are some example sentences to help you improve your vocabulary:
In the present study, while we cannot rule out the possibility that Btk:ER activates PLCγ2 in combination with other uncharacterized pathways, our data strongly support the Btk/PLCγ2 signalosome model by showing that PLCγ2 is absolutely required for Btk:ER-induced calcium, MAPK and apoptosis responses.
In Fig 5we have tested whether PLCγ2 is required for Btk:ER-induced ERK and JNK activation, and apoptosis.
To test whether PLCγ2 is required for Btk:ER-induced calcium mobilization, parental and PLCγ2-deficient cells expressing Btk:ER were treated with 4-HT and/or anti-μ, or ionomycin as a positive control (Fig 4B).
A functional kinase domain was required for Btk:ER-induced apoptosis, as kinase inactive Btk:ER failed to induce apoptosis in response to either 4-HT or anti-μ stimulation (Fig 3C).
In Fig 5Cwe have investigated the mechanism by measuring Btk:ER-induced apoptosis in parental and PLCγ2-deficient cells.