Words similar to epks

Example sentences for: epks

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EPKs frequently contain one or more non-catalytic domains, some of which are thought to serve for docking EPKs to various constituents of these complexes.
In vitro, purified EPKs often display broad protein substrate specificity [ 7], and it is thought that in many cases in vivo substrate specificity is limited by a requirement for substrate to associate not only with its cognate EPK, but also with other components of an EPK-containing protein assembly [ 8, 33, 34].
Four hundred EPKs could be associated with a Human Genome Organization (HUGO) Gene Nomenclature Committee (HGNC) [ 55] name (such as MAPgK11, RAF1 or PRKCM) or description that implies previous knowledge about the potential function or subfamily membership of the sequence.
The solution of crystal structures for several EPKs, some of which include bound ATP and protein substrate, has clarified the functional role of particular conserved residues in binding different portions of ATP and protein substrate molecules, and in regulating these binding events [ 12, 13, 14, 15, 16].
One frequently reported mechanism for regulating EPK activity involves phosphorylation of key residues of the EPK catalytic domain by other upstream EPKs [ 13, 29, 30, 31, 32].